中枢神经系统厌氧菌感染的治疗现状  

Treatment status of anaerobic infection in central nervous system

作　　者：郝文文 刘雅菁 冯双浩 卜晖[1] 何俊瑛[1] HAO Wenwen;LIU Yajing;FENG Shuanghao(Department of Neurology,the Second Hospital of Hebei Medical University,Shijiazhuang 050000,China)

机构地区：[1]河北医科大学第二医院神经内科,石家庄050000

出　　处：《临床神经病学杂志》2024年第6期456-459,共4页Journal of Clinical Neurology

摘　　要：厌氧菌通常被认为是一类只能在低氧分压的条件下生长,不能在空气(或含18%氧气)和/或10%二氧化碳浓度下固体培养基表面生长的细菌。厌氧菌可通过临近头部与颈部的感染灶、血行播散、颅脑外伤等方式扩散至CNS,引起局灶性化脓性感染,如颅内脓肿(脑脓肿、硬膜外脓肿和硬膜下脓肿),而厌氧菌引起的脑膜炎较少见。本文对CNS厌氧菌感染的手术治疗、抗生素选择及其他治疗方式进行阐述。Anaerobic bacteria are commonly classified as a distinct group of microorganisms capable of proliferation solely in environments with reduced oxygen tension,and are incapable of growth on the surface of solid media containing atmospheric air(equivalent to 18%oxygen)and/or 10%carbon dioxide.These bacteria have the potential to infiltrate the central nervous system via adjacent infections in the head and neck region,hematogenous dissemination,or cranial-cerebral trauma,leading to localized purulent infections,such as intracranial abscesses,which include cerebral abscesses,epidural abscesses,and subdural abscesses.Although meningitis caused by anaerobic bacteria is relatively rare,it remains a significant clinical concern.The present study comprehensively discusses the surgical interventions for central nervous system infections due to anaerobic bacteria,as well as the strategic selection and utilization of antibiotics and alternative therapeutic modalities.

关 键 词：厌氧菌 CNS 治疗 

分 类 号：R51[医药卫生—内科学]