基于“伏毒”理论的儿童免疫性血小板减少症诊疗思路探赜  

Exploration of the Diagnosis and Treatment Ideas of Immune Thrombocytopenia in Children Based on“Latent Poison”Theory

作　　者：范淑华[1,2] 丁樱[1,2] 管志伟[1] FAN Shuhua;DING Ying;GUAN Zhiwei(Pediatric Hospital,The First Affiliated Hospital of Henan University of Chinese Medicine,Zhengzhou 450000,China;College of Pediatrics,Henan University of Chinese Medicine,Zhengzhou 450000,China)

机构地区：[1]河南中医药大学第一附属医院儿科医院,河南郑州450000 [2]河南中医药大学儿科医学院,河南郑州450000

出　　处：《南京中医药大学学报》2025年第2期160-168,共9页Journal of Nanjing University of Traditional Chinese Medicine

基　　金：第七批全国老中医药专家学术经验继承工作项目(国中医药人教函〔2022〕76号);国家中医药管理局国医大师传承工作室建设项目(国中医药办人教函〔2022〕245号)。

摘　　要：国医大师丁樱教授基于现代免疫学机制,运用中医取类比象法,化繁为简,将导致免疫性血小板减少症(ITP)发病的异常免疫反应称之为“伏毒”,认为伏毒内侵是ITP的发病基础,血损髓伤是ITP的病理本质,“毒-虚-瘀”转化是ITP的基本病机,并由此制定了“扶正、祛毒、化瘀”的治疗原则,重视藤类药物、炭类药物的应用,在临证中收获了较好的疗效。Based on the mechanism of modern immunology,Professor Ding Ying,a traditional Chinese medicine(TCM)master,uses the analogy of TCM to simplify the complex and calls the abnormal immune response that leads to the onset of immune thrombocytopenia(ITP)“latent poison”.She believes that the invasion of latent poison is the basis of ITP;blood damage and marrow injury are the pathological essence of ITP;and the transformation of“poison-deficiency-stasis”is the basic pathogenesis of ITP.She has formulated the treatment principle of“strengthening healthy qi,removing poison,and removing stasis”,and attaches importance to the application of rattan drugs and charcoal drugs,which has achieved good results in clinical practice.

关 键 词：免疫性血小板减少症 儿童 伏毒 损血伤髓 病机 丁樱 名医经验 

分 类 号：R249[医药卫生—中医临床基础]