红花八角茎叶中一个新的酚苷类化合物  

A New Phenolic Glycoside from the Stems and Leaves of Illicium Dunnianum

作　　者：颜月园[1] 张馨予 刘刚[1] 胡玉涛[1] YAN Yueyuan;ZHANG Xinyu;LIU Gang;HU Yutao(Lianyungang TCM Branch of Jiangsu Union Technical Institute,Lianyungang 222007,China)

机构地区：[1]江苏联合职业技术学院连云港中医药分院,江苏连云港222007

出　　处：《南京中医药大学学报》2025年第2期251-256,共6页Journal of Nanjing University of Traditional Chinese Medicine

基　　金：江苏省中医药局科技项目(YB2017068)。

摘　　要：目的对红花八角Illicium dunnianum Tutcher干燥地上部分的茎叶进行化学成分研究。方法综合运用AB-8、硅胶、HW-40C、ODS、Sephadex LH-20和半制备HPLC等多种色谱学方法进行分离纯化,并根据化合物的理化性质和核磁共振波谱数据及ECD计算进行结构鉴定。结果从红花八角茎叶70%乙醇提取物经HP-20大孔吸附树脂30%乙醇洗脱部位中共分离鉴定5个化合物,分别为茴香脑乙二醇-7-O-β-L-呋喃阿拉伯糖-(1→6)-β-D-葡萄糖苷(1)、苯甲醛-4-O-β-D-葡萄糖苷(2)、1-O-苯甲基-α-L-鼠李糖-(1→6)-β-D-葡萄糖苷(3)、1-O-苯甲酰基-β-D-葡萄糖苷(4)、Sachalinoside B(5)。结论化合物1为新的酚苷类化合物,2~5为首次从该属植物中分离得到。OBJECTIVE To study the constituents from the dried stems and leaves of Illicium dunnianum Tutcher.METHODS The compounds were isolated and purified by column chromatography of AB-8 macroporous resin,silica gel,HW-40C,ODS,Sephadex LH-20,and semi-preparative RP-HPLC.Their structures were elucidated by physicochemical properties,spectral analyses and ECD.RESULTS The 70%ethanol extract of Illicium dunnianum was subjected to AB-8 macroporous adsorption resin CC to yield 30%ethanol fraction.Five compounds were obtained and characterized as anisole glycol-7-O-β-L-funanarabifuranosyl-(1→6)-β-D-glucopyranoside(1),4-O-β-D-glucopyranosyloxy-benzaldehyde(2),benzyl-O-α-L-rhamnopyranosyl-(1→6)-β-D-glucopyranoside(3),β-D-glucopyranoside benzoate(4)and sachalinoside B(5),respectively.CONCLUSION Compound 1 is a new phenolic glycoside,2-5 are identified from Illicium dunnianum for the first time.

关 键 词：红花八角 茎叶 化学成分 结构鉴定 茴香脑乙二醇-7-O-β-L-呋喃阿拉伯糖-(1→6)-β-D-葡萄糖苷 酚苷类 

分 类 号：R284[医药卫生—中药学]