妊娠合并亚临床甲状腺功能减退症的早期治疗对妊娠结局的影响  

The Impact of Early Treatment of Subclinical Hypothyroidism in Pregnancy on Pregnancy Outcomes

作　　者：夏岚 Lan Xia(Zhongxian Maternal and Child Health Hospital,Chongqing 400000)

机构地区：[1]忠县妇幼保健院,重庆400000

出　　处：《医学研究前沿》2024年第11期23-25,共3页Frontiers of Medical Research

摘　　要：目的探讨妊娠合并亚临床甲状腺功能减退症(SCH)的早期左旋甲状腺素(LT4)干预治疗对妊娠结局的影响。方法回顾性分析2021年1月至2022年12月在我院产科就诊的妊娠合并SCH的单胎初产妇112例,根据是否在妊娠12周内开始接受LT4治疗分为治疗组和对照组,每组56例。结果两组患者的年龄、孕周、TSH及FT4水平等一般资料比较,差异均无统计学意义(P>0.05)。结论对于妊娠合并SCH的患者,在妊娠早期(12周内)给予适量LT4治疗,可显著改善母婴预后,降低妊娠及新生儿并发症发生风险。Objective To investigate the effect of early levothyroxine(LT4)intervention on pregnancy outcomes in patients with subclinical hypothyroidism(SCH)during pregnancy.Method A retrospective analysis was conducted on 112 singleton primiparous women with SCH who visited our obstetrics department from January 2021 to December 2022.They were divided into a treatment group and a control group based on whether they started receiving LT4 treatment within 12 weeks of pregnancy,with 56 cases in each group.Result There was no statistically significant difference in general information such as age,gestational age,TSH,and FT4 levels between the two groups of patients(P>0.05).Conclusion For patients with SCH during pregnancy,appropriate treatment with LT4 during early pregnancy(within 12 weeks)can significantly improve maternal and infant prognosis and reduce the risk of pregnancy and neonatal complications.

关 键 词：亚临床甲状腺功能减退症 妊娠 左旋甲状腺素 

分 类 号：R714.25[医药卫生—妇产科学]