云南省2006-2023年边境地区百日咳流行病学特征  

Epidemiological characteristics of pertussis in border areas of Yunnan Province from 2006 to 2023

作　　者：朱琴 邱钰婷 赵智娴[2] 余文[2] 唐婷婷[2] ZHU Qin;QIU Yuting;ZHAO Zhixian;YU Wen;TANG Tingting(Public Health School of Dali University,Dalil Yunnan675000,China;Immunization Program Institute of Yunnan CDC,Kunming Yunnan 650500,China)

机构地区：[1]大理大学公共卫生学院,云南大理675000 [2]云南省疾病预防控制中心免疫规划所,云南昆明650500

出　　处：《云南医药》2025年第1期15-19,共5页Medicine and Pharmacy of Yunnan

基　　金：云南省疾病预防控制中心科技计划项目(2022ZX004);云南省四州市百日咳流行趋势及分子流行病学研究项目(2023ZX007)。

摘　　要：目的分析云南省2006-2023年8个边境州(市)百日咳流行病学特征。方法通过中国疾病预防控制信息系统传染病监测系统收集云南省2006-2023年8个边境州(市)百日咳报告病例,运用描述性方法分析流行病学特征。结果2006-2023年8个边境州(市)平均年发病率为0.32/10万(0.05/10万~1.38/10万),实验室确诊病例呈升高趋势。男女比为1.19∶1。主要发病季节为春夏季、3~17月龄散居儿童高发。以云南省免疫规划信息系统记录为依据,查询到百日咳病例接种个案信息608例,接种百白破疫苗0剂次、1剂次、2剂次、3剂次、4剂次的占比分别为58.3%、11.1%、4.1%、7.8%、18.7%;≥4月龄、≥5月龄的病例中分别有47.4%、48.7%的病例未及时按照国家免疫接种程序接种DTP,≥18月龄病例中有25.3%未全程接种DTP。结论云南省2006-2023年8个边境州(市)百日咳发病整体呈上升趋势,但发病水平可能被低估。应加强边境地区百日咳疫苗接种工作,提高疫苗接种率。定期开展百日咳防治知识的宣传,提高边境地区居民对百日咳的认知。Objective To analyze the epidemiological characteristics of pertussis in eight border prefectures(cities)in Yunnan Province from 2006 to 2023.Methods Pertussis reported cases in eight border prefectures(cities)in Yunnan Province from 2006 to 2023 were collected through the infectious disease surveillance system of China Center for Disease Control and Prevention Information System,and the epidemiological characteristics were analyzed by descriptive methods.Results From 2006 to 2023,the average annual incidence rate in the eight border prefectures(cities)was 0.32/100,000(ranging from 0.05/100,000 to 1.38/100,000),and the number of laboratory-confirmed cases showed an increasing trend.The male-to-female ratio was 1.19∶1,and main incidence season was spring and summer,and the incidence was high among scattered children age 3 to 17 months.Based on the records of Yunnan Provincial immunization program information system,608 individual vaccination information cases of pertussis were found.The proportions of cases vaccinated with 0 dose,1 dose,2 doses,3 doses and 4 doses of DPT vaccine were 58.3%,11.1%,4.1%,7.8%and 18.7%,respectively.47.4%and 48.7%of the cases aged≥4 months and≥5 months,were not vaccinated with DTP in time according to the national immunization schedule,and 25.3%cases aged≥18 months were not fully vaccinated with DTP.Conclusions From 2006 to 2023,the overall incidence of pertussis in the eight border prefectures(cities)in Yunnan Province showed an upward trend,but the incidence level may be underestimated.The pertussis vaccination work in border areas should be strengthened to improve the vaccination rate.Regular publicity on pertussis prevention and control knowledge should be carried out to improve the awareness of pertussis among residents in border areas.

关 键 词：百日咳 流行病学特征 云南边境 

分 类 号：R181.3[医药卫生—流行病学] R516.6[医药卫生—公共卫生与预防医学]