海南省消除病毒性肝炎公共卫生危害工作实践  

Working practices in eliminating the public health crisis caused by viral hepatitis in Hainan Province of China

作　　者：李维华 熊昌富[2] 陈太梵 何滨[2] 殷大鹏 曾雪霞[3] 林锋[4] 陈碧玉[5] 曾小妹[5] 吴彪 江娟 钟璐 张毓辉 LI Weihua;XIONG Changfu;CHEN Taifan;HE Bin;YIN Dapeng;ZENG Xuexia;LIN Feng;CHEN Biyu;ZENG Xiaomei;WU Biao;JIANG Juan;ZHONG Lu;ZHANG Yuhui(Department of Primary Health Care,Hainan Provincial Health Commission,Haikou 570203,China;Hainan Provincial Center for Disease Control and Prevention,Haikou 571129,China;Department of Scientific Research Information,Hainan Provincial Center for Disease Control and Prevention,Haikou 571129,China;Hainan Provincial People’s Hospital,Haikou 570311,China;Institute for the Prevention and Control of Infectious Diseases,Hainan Provincial Center for Disease Control and Prevention,Haikou 571129,China;Hainan Public Health Clinical Center,Haikou 571129,China;Institute for the Prevention and Control of Tropical Diseases and Chronic Diseases,Hainan Provincial Center for Disease Control and Prevention,Haikou 571129,China;Hainan Provincial Health Commission,Haikou 570203,China)

机构地区：[1]海南省卫生健康委员会基层卫生健康处,海口570203 [2]海南省疾病预防控制中心,海口571129 [3]海南省疾病预防控制中心科研信息处,海口571129 [4]海南省人民医院,海口570311 [5]海南省疾病预防控制中心传染病预防控制所,海口571129 [6]海南省公共卫生临床中心,海口571129 [7]海南省疾病预防控制中心热带病与慢性病预防控制所,海口571129 [8]海南省卫生健康委员会,海口570203

出　　处：《临床肝胆病杂志》2025年第2期228-233,共6页Journal of Clinical Hepatology

摘　　要：2022年海南省政府启动了病毒性肝炎防治项目,其目标为:到2025年底18岁以上人群乙型肝炎筛查率达到90%,诊断率达到90%,治疗率达到80%;其主要干预措施为“人群预防、病例筛查、抗病毒治疗和健康管理”。截至2024年12月31日,累计筛查乙型肝炎大众人群687.5万人,筛查率为95.6%;发现HBs Ag阳性者184710例,其中确诊复核检测156772例,诊断率为84.9%;发现慢性乙型肝炎患者50742例,其中建立乙型肝炎专病档案进行健康管理42921例,建档率84.6%;抗病毒治疗31553例,治疗率62.2%。累计筛查丙型肝炎重点人群250.3万人,其中抗-HCV阳性4870例,HCV RNA检测3858例,诊断率为79.2%;发现HCV RNA阳性1824例,其中接受抗病毒治疗1194例,治疗率65.5%。对HBsAg和抗-HBs阴性、年龄在20~40岁人群免费接种乙型肝炎疫苗159301人。通过病毒性肝炎防治项目的实施,海南省短期内发现、治疗和管理了一大批病毒性肝炎患者,明显加快了消除病毒性肝炎危害行动步伐。In 2022,Hainan provincial government launched the project for the prevention and control of viral hepatitis with the goals of a hepatitis B screening rate of 90%,a diagnostic rate of 90%,and a treatment rate of 80%among people aged 18 years and above by the year 2025,and the main intervention measures include population-based prevention,case screening,antiviral therapy,and health management.As of December 31,2024,a total of 6.875 million individuals in the general population had been screened for hepatitis B,with a screening rate of 95.6%.A total of 184710 individuals with positive HBsAg were identified,among whom 156772 were diagnosed through serological reexamination,resulting in a diagnostic rate of 84.9%.A total of 50742 patients with chronic hepatitis B were identified,among whom 42921 had hepatitis B-specific health records established for health management,with a file establishment rate of 84.6%.A total of 31553 individuals received antiviral therapy,with a treatment rate of 62.2%.A total of 2.503 million individuals at a high risk of hepatitis C were screened,among whom 4870 tested positive for HCV antibody and 3858 underwent HCV RNA testing,resulting in a diagnostic rate of 79.2%,and 1824 individuals with positive HCV RNA were identified,among whom 1194 received antiviral therapy,with a treatment rate of 65.5%.In addition,159301 individuals with negative HBsAg and anti-HBs and an age of 20-40 years were inoculated with hepatitis B vaccine free of charge.Through the implementation of the project for the prevention and control of viral hepatitis,a large number of hepatitis patients have been identified,treated,and managed in the province within a short period of time,which significantly accelerates the efforts to eliminate the crisis of viral hepatitis.

关 键 词：肝炎 病毒性 人 公共卫生工作 海南 

分 类 号：R512.6[医药卫生—内科学]