Z分数在核酸检测室间质评回顾性分析中的应用  

Application of Z-score in retrospective analysis of external quality assessment for nucleic acid testing

作　　者：魏玮 魏嬴 WEI Wei;WEI Ying(Xuzhou Blood Center,Xuzhou 221006,China)

机构地区：[1]徐州市红十字血液中心,江苏徐州221006

出　　处：《中国输血杂志》2025年第2期244-250,256,共8页Chinese Journal of Blood Transfusion

摘　　要：目的 将Z分数作为室间质评(EQA)结果评价的手段,提高实验室的质量控制管理能力。方法 依据2021—2023年国家卫健委临床检验中心核酸EQA反馈结果绘制Z分数质控图,采用Westgard质控规则进行室间质量评价管理。结果 2021—2023年EQA中罗氏检测系统HBV标本混样检测发生了失控,其余项目均在控;科华检测系统HCV标本混样检测、HBV标本拆分检测发生了失控,HIV标本拆分检测出现了警告,其余项目均在控。结论 Z分数质控图可实现EQA结果的连续监测,采用Westgard质控规则进行质量评价管理,能够提示误差的类型,有助于提升实验室质量管理控制能力,确保实验室核酸检测结果的准确性。Objective To use the Z-scores as a means of evaluating the results of external quality assessment(EQA),so as to improve the quality control management in laboratories.Methods Z-scores control charts were plotted based on the feedback results of nucleic acids EQA from the National Center for Clinical Laboratories from 2021 to 2023,and EQA management was conducted using Westgard quality control rules.Results In the EQA from 2021 to 2023,the Roche testing system experienced runaway event in the HBV sample minipool testing,while all other items were under control.For KH testing system,runaway events occurred in HCV sample minipool testing and HBV samples resolution,and a warning was issued for the resolution detection of HIV samples,while other items were under control.Conclusion The Z-score control chart can achieve continuous monitoring of EQA results,and the use of Westgard quality control rules for quality assessment management can identify the types of errors,which can help enhance the laboratory’s quality management and control capabilities,and ensure the accuracy of laboratory nucleic acid test results.

关 键 词：Z分数 核酸检测 室间质评 

分 类 号：R457[医药卫生—治疗学] R446[医药卫生—临床医学]