Adjacent Segment Biomechanical Changes After Implantation of Cage Plus Plate or Zero-Profile Device in Different Segmental Anterior Cervical Discectomy and Fusion  

作　　者：YE Peng FU Rongchang WANG Zhaoyao 叶鹏;富荣昌;王召耀(School of Mechanical Engineering,Xinjiang University,Urumqi,830017,China)

机构地区：[1]School of Mechanical Engineering,Xinjiang University,Urumqi,830017,China

出　　处：《Journal of Shanghai Jiaotong university(Science)》2025年第1期166-174,共9页上海交通大学学报(英文版)

基　　金：the National Natural Science Foundation of China(Nos.32260235 and 82260446)。

摘　　要：Cage plus plate(CP)and zero-profile(Zero-P)devices are widely used in anterior cervical discectomy and fusion(ACDF).This study aimed to compare adjacent segment biomechanical changes after ACDF when using Zero-P device and CP in different segments.First,complete C1—C7 cervical segments were constructed and validated.Meanwhile,four surgery models were developed by implanting the Zero-P device or CP into C4—C5 or C5—C6 segments based on the intact model.The segmental range of motion(ROM)and maximum value of the intradiscal pressure of the surgery models were compared with those of the intact model.The implantation of CP and Zero-P devices in C4—C5 segments decreased ROM by about 91.6%and 84.3%,respectively,and increased adjacent segment ROM by about 8.3%and 6.82%,respectively.The implantation of CP and Zero-P devices in C5—C6 segments decreased ROM by about 93.3%and 89.9%,respectively,while increasing adjacent segment ROM by about 4.9%and 4%,respectively.Furthermore,the implantation of CP and Zero-P devices increased the intradiscal pressure in the adjacent segments of C4—C5 segments by about 4.5%and 6.7%,respectively.The implantation of CP and Zero-P devices significantly increased the intradiscal pressure in the adjacent segments of C5—C6 by about 54.1%and 15.4%,respectively.In conclusion,CP and Zero-P fusion systems can significantly reduce the ROM of the fusion implant segment in ACDF while increasing the ROM and intradiscal pressure of adjacent segments.Results showed that Zero-P fusion system is the best choice for C5—C6 segmental ACDF.However,further studies are needed to select the most suitable cervical fusion system for C4—C5 segmental ACDF.Therefore,this study provides biomechanical recommendations for clinical surgery.

关 键 词：BIOMECHANICS finite element analysis adjacent segment degeneration range of motion(ROM) intradiscal pressure 

分 类 号：R318.01[医药卫生—生物医学工程]