醋酸亮丙瑞林微球在子宫内膜异位症手术患者中的应用价值分析  

The application value of Leuprorelin Acetate Microspheres in patients undergoing endometriosis surgery

作　　者：蒋键泓 Jiang Jianhong(Department of Pharmacy,The Second People's Hospital of Wuxi Huishan District(Wuxi Second Geriatric Hospital),Wuxi 214174,Chinal)

机构地区：[1]无锡市惠山区第二人民医院(无锡市第二老年病医院)药剂科,江苏无锡214174

出　　处：《实用妇科内分泌电子杂志》2024年第21期28-30,共3页Electronic Journal of Practical Gynecological Endocrinology

摘　　要：目的深入分析醋酸亮丙瑞林微球应用于子宫内膜异位症手术患者的效果。方法选取子宫内膜异位症患者共50例,应用双盲法将其分组,每组25例。对照组予以炔雌醇环丙孕酮片治疗,研究组予以醋酸亮丙瑞林微球治疗。比较两组手术疗效、性激素水平及副作用情况。结果研究组总有效率高于对照组(P<0.05)。研究组患者促黄体生成素(LH)、雌二醇(E_(2))及促卵泡生成素(FSH)水平均低于对照组(P<0.05)。研究组不良反应发生率低于对照组(P<0.05)。结论醋酸亮丙瑞林微球在子宫内膜异位症治疗中疗效显著,性激素水平调节效果较好,且安全性较高,可促进快速康复,值得临床推广与应用。Objective To analyze the effect of Leuprorelin Acetate Microspheres on patients undergoing endometriosis surgery.Methods 50 patients with endometriosis were selected and divided into 25 patients each by double-blind method.The control group was treated with ethinestradiol cyproterone tablets,and the study group was treated with Leuprorelin Acetate Microspheres.The curative effect,sex hormone levels and side effects were compared between the two groups.Results The total effective rate of the study group was higher than that of the control group(P<0.05).The levels of luteinizing hormone(LH),estradiol(E_(2))and follicle-stimulating hormone(FSH)in study group were lower than those in control group(P<0.05).The incidence of adverse reactions in the study group was significantly lower than that in the control group(P<0.05).Conclusion Leuprorelin Acetate Microspheres have significant curative effect in the treatment of endometriosis,with better regulation effect on sex hormone levels and high safety,which can promote rapid recovery and is worthy of clinical promotion and application.

关 键 词：子宫内膜异位症 醋酸亮丙瑞林微球 性激素 治疗效果 安全性 

分 类 号：R713.4[医药卫生—妇产科学]