fMRI在脑卒中康复期脑网络重塑与脑可塑性中的研究进展  

Research progress of fMRI in brain plasticity during the rehabilitation period of hemiplegia after stroke

作　　者：李锡君 余成新[1,2] 赵长江[1,2] 潘君龙[1,2] LI Xijun;YU Chengxin;ZHAO Changjiang;PAN Junlong(The First College of Clinical Medical Science,China Three Gorges University,Yichang 443000,China;Department of Radiology,Yichang Central People's Hospital,Yichang 443000,China)

机构地区：[1]三峡大学第一临床医学院,宜昌443000 [2]宜昌市中心人民医院放射科,宜昌443000

出　　处：《磁共振成像》2025年第2期135-141,共7页Chinese Journal of Magnetic Resonance Imaging

基　　金：北京医学奖励基金会基金项目(编号:YXJL-2022-0105-0134)。

摘　　要：脑卒中是全球主要的致残原因之一,可导致患者在运动、感觉及认知功能上出现障碍。传统的康复治疗周期长、见效慢,而近年来脑机接口、健侧第七颈神经移位术、脑刺激和细胞治疗等技术在卒中患者群体中的应用旨在增强脑可塑性、缓解症状,为临床提供了新的治疗思路。功能磁共振成像(functional magnetic resonance imaging,fMRI)作为脑科学重要的研究工具之一,已经广泛应用于脑卒中康复的研究中,它不仅能描述功能和网络连接变化,还能预测康复预后、指导治疗方案和监测康复效果,为脑卒中康复治疗提供了理论依据。本综述总结了近年来国内外应用fMRI技术在脑卒中康复期脑网络重塑等方面的探索,分析了相关研究成果以及存在的难点,以期为脑卒中康复治疗的fMRI研究提供新的思路。Stroke is one of the main causes of disability in the world,which can lead to motor,sensory and cognitive impairments in patients.Traditional rehabilitation treatment cycle is long and has slow effect.In recent years,the application of brain-computer interface,healthy cervical nerve transfer,brain stimulation and cell therapy in stroke patients is to enhance brain plasticity and relieve symptoms.Provides new treatment ideas for clinical practice.Functional magnetic resonance imaging(fMRI)is one of the important research tools in brain science and has been widely used in the research on stroke rehabilitation.It can not only describe functional and network connection changes,but also predict rehabilitation prognosis,guide treatment plans and monitoring the rehabilitation effect provides a theoretical basis for rehabilitation treatment of stroke.This review summarizes the exploration of the application of fMRI technology at home and abroad in recent years in brain network remodeling,analyzes relevant research results and existing difficulties,in order to provide new ideas for fMRI research on stroke rehabilitation treatment.

关 键 词：脑卒中 磁共振成像 功能磁共振成像 大脑可塑性 脑网络重塑 功能连接 皮质脊髓束完整性 

分 类 号：R445.2[医药卫生—影像医学与核医学] R743.3[医药卫生—诊断学]