事件相关电位评估重复性亚脑震荡后认知损害的研究进展  

Advances in the evaluation of cognitive impairment after repeated subconcussion using event-related potentials

作　　者：张浩然 周阳 王铄辰 宋健 ZHANG Hao-ran;ZHOU Yang;WANG Shuo-chen;SONG Jian(School of Medicine,Wuhan University of Science and Technology,Wuhan 430081,China;Department of Neurosurgery,General Hospital of Central Theater Command,PLA,Wuhan 430070,China;Hubei University of Medicine,Shiyan 442000,China)

机构地区：[1]武汉科技大学医学院,武汉430081 [2]中国人民解放军中部战区总医院神经外科,武汉430070 [3]湖北医药学院,湖北十堰442000

出　　处：《中国临床神经外科杂志》2024年第12期742-746,共5页Chinese Journal of Clinical Neurosurgery

摘　　要：重复性亚脑震荡是指头部受到反复的轻微撞击产生的脑损伤。虽然单次轻微撞击不足以引发明确的脑震荡症状,但是多次轻微撞击就会对大脑造成损伤。重复性亚脑震荡与长期神经功能改变和累积性脑损伤密切相关,可能增加神经退行性疾病的风险,从而导致认知功能的改变,使晚年的生活质量下降。事件相关电位技术可以客观地、准确地评估脑功能在重复性亚脑震荡暴露下的变化。本综述对近年来重复性亚脑震荡相关的事件相关电位研究进行回顾总结,为理解重复性亚脑震荡暴露损伤的神经机制提供参考。Repetitive subconcussive concussion refers to brain injury resulting from repeated minor head impacts.Although a single minor impact is insufficient to induce definite concussion symptoms,multiple minor impacts can cause damage to the brain.Repetitive subconcussive concussion is closely associated with long-term neurofunctional alterations and cumulative brain injuries,potentially increasing the risk of neurodegenerative diseases,thereby resulting in changes in cognitive function and a decline in the quality of life in later years.Event-related potential technology can objectively and precisely evaluate the changes in brain function under repetitive subconcussive concussion exposure.This review summarizes the event-related potential studies related to repetitive subconcussive concussion in recent years,providing a reference for understanding the neural mechanisms of repetitive subconcussive concussion exposure-induced damage.

关 键 词：重复性亚脑震荡 认知损害 事件相关电位 

分 类 号：R651.15[医药卫生—外科学]