低能量体外冲击波在勃起功能障碍中的应用及其机制的研究进展  

Low-intensity extracorporeal shock wave therapy for erectile dysfunction:Updated action mechanisms and application

作　　者：徐海中 宁艺萍(综述) 杨旭凯(审校) XU Hai-zhong;NING Yi-ping;YANG Xu-kai(The First School of Clinical Medicine,Gansu University of Chinese Medicine,Lanzhou,Gansu 730000,China;Department of Urology,No.940 Hospital of Chinese People's Liberation Army,Lanzhou,Gansu 730050,China)

机构地区：[1]甘肃中医药大学第一临床医学院,甘肃兰州730000 [2]解放军第九四〇医院泌尿外科,甘肃兰州730050

出　　处：《中华男科学杂志》2025年第1期69-75,共7页National Journal of Andrology

基　　金：兰州市人才创新创业项目(2021-RC-106)。

摘　　要：勃起功能障碍(ED)是多因素引起的一种常见性功能障碍疾病,磷酸二酯酶-5抑制剂(PDE5i)虽是治疗ED常用的药物,但对于中重度及患有糖尿病等基础性疾病的患者往往疗效不佳。低能量体外冲击波治疗(Li-ESWT)是一种新型非侵入性物理治疗,具有组织损伤小、安全性高、治疗周期短等优点。经过十多年间研究发展,Li-ESWT治疗ED的有效性和安全性得到初步论证,对PDE5i疗效不佳的ED患者,改用Li-ESWT后症状改善显著。国内外对Li-ESWT的研究日益增多,其在ED治疗领域中的应用成为目前关注的热点。本文阐述了Li-ESWT在ED治疗中的作用机制及应用情况,为ED患者的临床诊治提供新思路。Erectile dysfunction(ED)is a most common sexual dysfunction caused by various factors.Phosphodiesterase-5 inhibitors(PDE5i)are commonly used for the treatment of ED,but often with a poor effect for patients with moderate to severe ED and those with underlying diseases such as diabetes mellitus.Low-intensity extracorporeal shock wave therapy(Li-ESWT),as a novel non-invasive physical therapy,has the advantages of mild tissue damage,high safety and short treatment cycle.The effectiveness and safety of Li-ESWT in the treatment of ED has been preliminarily demonstrated by more than a decade of research and development,and its therapeutic effect evidently exhibited by significantly improving the symptoms of the ED patients with poor response to PDE5i.Researches on Li-ESWT are increasing at home and abroad,and its application in the treatment of ED has become a hot spot of attention.This review elaborates the action mechanisms and application of Li-ESWT in the treatment of ED,aiming to provide some new ideas for the clinical diagnosis and treatment of the condition.

关 键 词：勃起功能障碍 低能量体外冲击波治疗 磷酸二酯酶-5抑制剂 

分 类 号：R698.2[医药卫生—泌尿科学]