泛免疫炎症值对术前老年结直肠癌病人衰弱的预测价值  

Predictive value of pan⁃immune inflammation value for the frailty of elderly patients with colorectal cancer before operation

作　　者：张思苑 高欢玲[1] 刘利红 于银梅 李红梅[1] 马彩虹 崔彩彩 吕旭晶 ZHANG Siyuan;GAO Huanling*;LIU Lihong;YU Yinmei;LI Hongmei;MA Caihong;CUI Caicai;LYU Xujing(Fenyang College,Shanxi Medical University,Shanxi 032200 China;Shanxi Province Fenyang Hospital)

机构地区：[1]山西医科大学汾阳学院,山西032200 [2]山西省汾阳医院

出　　处：《护理研究》2025年第5期753-760,共8页Chinese Nursing Research

基　　金：吕梁市科技计划项目,编号:2024SHFZ41。

摘　　要：目的:分析术前老年结直肠癌病人的衰弱现状及影响因素,并探讨泛免疫炎症值(PIV)对其预测价值。方法:选取山西省某三级甲等医院普外科与肿瘤科2022年12月—2023年12月的老年结直肠癌病人为研究对象,采用一般人口学资料和临床资料调查表、Fried衰弱表型、癌症病人生命质量测定量表体系之大肠癌量表、慢性病患者健康素养量表收集资料。采用Logistic回归分析术前老年结直肠癌病人衰弱的影响因素,并利用受试者工作特征(ROC)曲线分析PIV对其预测价值。结果:共纳入277例老年结直肠癌病人,其中衰弱病人占39.4%;Logistic回归结果显示,年龄、性别、体质指数(BMI)、白蛋白水平、PIV、生活质量与健康素养为术前老年结直肠癌病人衰弱的影响因素(P<0.05)。ROC曲线分析结果显示,PIV预测衰弱的曲线下面积为0.815,PIV最佳截断值为355.69,敏感度为78.9%,特异度为84.5%。结论:术前老年结直肠癌病人衰弱发生率高,临床应重视高龄、女性、BMI与白蛋白水平低、健康素养较低且结直肠癌特异性症状较明显的病人。同时,PIV对衰弱具有良好的预测作用。Objective:To analyze the status quo and influencing factors of frailty in elderly patients with colorectal cancer before operation,and to explore the predictive value of pan-immune inflammation value(PIV).Methods:A convenience sample of 277 elderly colorectal cancer patients was recruited from the departments of general surgery and oncology at a tertiary grade A hospital in Shanxi province between December 2022 and December 2023,and the data were collected using the questionnaire of general demographic data and clinical data,Frailty Phenotype,Health Literacy Scale for Chronic Patients,Quality of Life Instruments for Cancer Patients Colorectal Cancer.Logistic regression analysis were carried out to identify the influencing factors of frailty in senile colorectal cancer patients before operation,and the predictive value of PIV was analyzed by ROC curve.Results:A total of 277 elderly patients with colorectal cancer were included,of which 39.4%were patients with frailty.The results of binary Logistic regression showed that age,gender,BMI,albumin level,PIV,quality of life and health literacy of colorectal cancer patients were the influencing factors of frailty in senile patients with colorectal cancer before operation(P<0.05).ROC curve analysis shows that the AUC of PIV was 0.815,the best cutoff value was 355.69,the sensitivity was 78.9%,and the specificity was 84.5%.Conclusion:The incidence of frailty was high in elderly patients with colorectal cancer before operation,and clinical attention should be paid to elderly,female,low BMI and albumin levels,low health literacy,and more obvious colorectal cancer specific symptoms.Meanwhile,the PIV has a good predictive effect on frailty.

关 键 词：结直肠癌 老年人 衰弱 泛免疫炎症值 影响因素 预测 护理 

分 类 号：R473.73[医药卫生—护理学]