低能量冲击波治疗阴茎硬结症的临床效果  

Clinical effect of low intensity extracorporeal shock wave therapy for Peyronie's disease

作　　者：杜宇轩 周晨妤 陈晓峰 朱双菊 卞军 赖德辉[2] 梁雁冰 Du Yuxuan;Zhou Chenyu;Chen Xiaofeng;Zhu Shuangju;Bian Jun;Lai Dehui;Liang Yanbing(Guangzhou Medical University,Guangzhou 511436,China;Department of Urology,The Fifth Affiliated Hospital of Guangzhou Medical University,Guangzhou 510000,China)

机构地区：[1]广州医科大学,广州511436 [2]广州医科大学附属第五医院泌尿外科,广州510000

出　　处：《国际医药卫生导报》2025年第5期738-741,共4页International Medicine and Health Guidance News

基　　金：广州市科技计划(202201010834);广东省自然科学基金(2021A1515010065);2022年教育部产学合作协同育人项目(220904082210823)。

摘　　要：目的分析低能量冲击波治疗阴茎硬结症的临床效果。方法对2019年5月至2024年3月在广州医科大学附属第五医院泌尿外科诊断为阴茎硬结症的22例患者应用低能量冲击波进行治疗(每周1次,疗程4~12周),疗程结束后对患者硬结尺寸、阴茎弯曲程度、视觉模拟评分法(Visual Analogue Scale,VAS)评分、国际勃起功能指数调查问卷表-5(International Index of Erectile Function Questionnaire-5,IIEF-5)评分、并发症等进行记录。采用χ^(2)检验或Fisher确切概率法进行统计学分析。结果患者年龄32~55岁,平均年龄43.5岁;40岁以下6例(27.3%),40~50岁12例(54.5%),50岁以上4例(18.2%)。平均病程16个月;病程1年内10例(45.4%),1~2年8例(36.4%),超过2年4例(18.2%)。14例(63.6%)仅有1枚硬结,6例(27.3%)有2枚硬结,2例(9.1%)有3枚硬结。硬结大多呈结节状,仅4枚呈长条索状。硬结最大为25mm×23mm,最小为5mm×5mm。硬结分布于阴茎两侧8例(36.4%),分布于阴茎背侧14例(63.6%)。18例患者(81.82%)在疗程结束后出现了尺寸变小或变软的现象;18例有阴茎勃起疼痛的患者中,14例(77.78%)得到减轻;8例阴茎勃起后明显弯曲的患者中,6例(75.00%)治疗后改善;9例有勃起功能障碍的患者中,7例(77.78%)改善。所有患者均未见明显并发症。结论低能量冲击波治疗有助于缓解阴茎硬结导致的疼痛,改善阴茎弯曲,提高患者生活质量,值得进一步推广应用。Objective To analyze the clinical effect of low intensity extracorporeal shock wave therapy for Peyronie's disease.Methods A total of 22 patients diagnosed with Peyronie's disease at the Department of Urology,the Fifth Affiliated Hospital of Guangzhou Medical University from May 2019 to March 2024 were treated with low intensity extracorporeal shock wave therapy(once a week for 4-12 weeks).After completing the treatment,the induration size,degree of penile curvature,Visual Analogue Scale(VAS)score,International Index of Erectile Function Questionnaire-5(IIEF-5)score,and complications were recorded.χ^(2) test or Fisher exact probability method were used for statistical analysis.Results The patients ranged in age from 32 to 55 years old,with an average of 43.5 years old.Among them,6 cases(27.3%)were under 40 years old,12 cases(54.5%)were 40-50 years old,and 4 cases(18.2%)were over 50 years old.The average course of disease was 16 months,10 cases(45.4%)within 1 year,8 cases(36.4%)of 1-2 years,and 4 cases(18.2%)over 2 years;14 cases(63.6%)had only 1 induration,6 cases(27.3%)had 2 indurations,and 2 cases(9.1%)had 3 indurations.Most of the indurations were nodules,and were long cords in only 4 cases.The maximum induration was 25 mm×23 mm,and the minimum was 5 mm × 5 mm. The induration was found on both sides of the penis in 8 cases (36.4%) and on thedorsal side of the penis in 14 cases (63.6%). In 18 patients (81.82%), the size decreased or becamesoft after treatment. Of the 18 patients experiencing pain during penile erection, 14 cases (77.78%)had pain relief. Of the 8 patients with obvious penile curvature during erection, 6 cases (75.00%)were significantly improved after treatment. Of the 9 patients with erectile dysfunction, 7 cases(77.78%) showed significant improvement. No significant complications were observed in allpatients. Conclusions Low intensity extracorporeal shock wave therapy is helpful to relieve thepain caused by penile induration, and improve the penile curvature and quality of life. The findings

关 键 词：阴茎硬结症 低能量冲击波治疗 临床效果 

分 类 号：R69[医药卫生—泌尿科学]