两种植物黄酮醇对动物肠道黏膜屏障的调控  

Modulation of intestinal mucosal barrier in animals by 2 plant flavonols

作　　者：张洁[1] 李康乐 付馨乐 张冶秋 梁焰晖 刘庆华[1] 高玉云[1] 庄绍龙 张婧 ZHANG Jie;LI Kangle;FU Xinyue;ZHANG Yeqiu;LIANG Yanhui;LIU Qinghua;GAO Yuyun;ZHUANG Shaolong;ZHANG Jing(College of Animal Science,Fujian Agriculture and Forestry University,Fuzhou,Fujian 350002,China;Fujian Hexing Ecological Agriculture Technology Co.,Ltd.,Quanzhou,Fujian 362801,China)

机构地区：[1]福建农林大学动物科学学院,福建福州350002 [2]福建禾兴生态农业科技有限公司,福建泉州362801

出　　处：《福建农林大学学报(自然科学版)》2025年第2期230-237,共8页Journal of Fujian Agriculture and Forestry University:Natural Science Edition

基　　金：福建省中青年教师教育科研项目(JAT210078);福建省现代家禽产业体系项目(2019—2022);泉港区科技特派员创新创业计划项目(2023KT06)。

摘　　要：肠道黏膜屏障是维持机体肠道稳态平衡和阻碍病原菌入侵的重要屏障,包括物理屏障、化学屏障、微生物屏障和免疫屏障4个部分,其结构和功能的完整性对维持动物肠道健康至关重要。肠道黏膜屏障损伤会导致肠道功能紊乱,影响机体健康。植物黄酮醇是自然界分布最广的类黄酮,越来越多的研究表明,黄酮醇具有调节肠道功能、减轻肠道炎症和抗氧化等作用。针对槲皮素和山奈酚两种典型的植物黄酮醇对动物肠道黏膜屏障生理调控作用及对畜禽动物的影响进行了综述,旨在为植物黄酮醇作为功能性饲料添加剂应用于畜禽养殖提供依据。Intestinal mucosa is an important barrier to maintaining the balance of intestinal homeostasis and preventing the invasion of pathogenic bacteria.The intestinal mucosal barrier consists of 4 parts,namely physical,chemical,immune and biological barri⁃ers,and its structural and functional integrity are crucial for maintaining the wholesome of animal′s intestinal tract.Damage to any of these parts will lead to intestinal dysfunction and affect the health of the organism.Plant flavonols are the most widely distributed fla⁃vonoids in nature,and an increasing number of studies have showed that flavonols can regulate intestinal function,and reduce intes⁃tinal inflammation and oxidation.In this paper,2 typical plant flavonol,kaempferol and quercetin,were reviewed for their physio⁃logical modulation of intestinal mucosal barrier in animals,and their effects on livestock and poultry animals,aiming to provide a scientific basis for the application of plant flavonols as functional feed additives in livestock and poultry farming.

关 键 词：植物黄酮醇 槲皮素 山奈酚 肠道黏膜屏障 畜禽 

分 类 号：S816.7[农业科学—饲料科学]