慢性稳定型心绞痛患者穴位动态变化与冠状动脉病变相关性研究  

Correlation study between dynamic changes in acupoints and coronary artery lesions in patients with chronic stable angina pectoris

作　　者：赵圣敏 伍静[1] 李倩[1] 黄守瑞 陶欢 杨羚 李玲[1] 李瑛 陈进[1] 张立[1] 孙鑫[1] ZHAO Shengmin;WU Jing;LI Qian;HUANG Shourui;TAO Huan;YANG Ling;LI Ling;LI Ying;CHEN Jin;ZHANG Li;SUN Xin(West China Hospital,Sichuan University,Chengdu 610041,China;West China School of Public Health and West China Fourth Hospital,Sichuan University,Chengdu 610041,China;Clinical Medicine College,Chengdu University of Traditional Chinese Medicine,Chengdu 610036,China)

机构地区：[1]四川大学华西医院,成都610041 [2]四川大学华西公共卫生学院/华西第四医院,成都610041 [3]成都中医药大学临床医学院,成都610036

出　　处：《中华中医药杂志》2025年第1期371-375,共5页China Journal of Traditional Chinese Medicine and Pharmacy

基　　金：国家自然科学基金项目(No.81590955)。

摘　　要：目的:探讨慢性稳定型心绞痛(CSAP)患者穴位敏化程度与冠脉病变支数的相关性。方法:采用横断面设计,调查CSAP患者近期冠状动脉造影结果,主要为冠脉病变支数。同时使用Von Frey检测器检测疾病相关穴位的压痛阈值,使用有序Logistic回归探讨两者之间的相关性。结果:共纳入166例患者。膻中、阴郄压痛阈值与冠脉病变支数呈负相关(膻中:OR=0.495,95%CI[0.303,0.811];阴郄:OR=0.509,95%CI[0.261,0.992]);督俞的压痛阈值与冠脉病变支数呈正相关(督俞:OR=2.183,95%CI[1.168,4.079])。结论:膻中、阴郄可能是CSAP患者的敏化穴位,未来可进一步在前瞻性高质量的诊断检查中探讨CSAP患者穴位敏化动态变化与疾病严重程度之间的相关性,以期更好地辅助临床诊疗。Objective:To explore the correlation between acupoint sensitization levels and the number of coronary artery lesions in patients with chronic stable angina pectoris(CSAP).Methods:A cross-sectional design was employed to investigate recent coronary angiography results in CSAP patients,primarily focusing on the number of coronary artery lesions.Simultaneously,Von Frey filaments were used to measure the pressure pain threshold of disease-related acupoints,and ordered Logistic regression was utilized to explore the correlation between the two.Results:A total of 166 patients were included.The pressure pain thresholds of Danzhong(CV17) and Yinxi(HT6) were negatively correlated with the number of coronary artery lesions(Danzhong:OR=0.495 95%CI [0.303,0.811]);Yinxi:OR=0.509(95%CI [0.261,0.992]).The pressure pain thresholds of Dushu(BL40) was positively correlated with the number of coronary artery lesions(Dushu:OR=2.183,95%CI [1.168,4.079]).Conclusion:Danzhong and Yinxi may be sensitized acupoints in patients with CSAP.Future prospective high-quality diagnostic studies can further investigate the correlation between dynamic changes in acupoint sensitization and disease severity in CSAP patients,aiming to better assist clinical diagnosis and treatment.

关 键 词：穴位敏化 痛敏 慢性稳定型心绞痛 压力痛阈值 冠状动脉造影术 

分 类 号：R246.1[医药卫生—针灸推拿学]