成年居民血清铁蛋白与代谢综合征的关联性分析  

Correlation between serum ferritin and metabolic syndrome among adult residents

作　　者：赵惠 管军 刘冰峰 周小琦[1] ZHAO Hui;GUAN Jun;LIU Bingfeng;ZHOU Xiaoqi(Wuhan Center for Disease Control and Prevention,Wuhan,Hubei 430015,China;Jiangan Center for Disease Control and Prevention,Wuhan,Hubei 430014,China)

机构地区：[1]武汉市疾病预防控制中心,湖北武汉430015 [2]武汉市江岸区疾病预防控制中心,湖北武汉430014

出　　处：《公共卫生与预防医学》2025年第2期95-99,共5页Journal of Public Health and Preventive Medicine

摘　　要：目的探讨血清铁蛋白与代谢综合征发生风险的相关性,为预防控制代谢综合征提供依据。方法数据来源于2022年中国居民营养与健康监测项目江岸区调查数据。选取399名成年居民为研究对象进行问卷调查、体格检查和生化指标检测。采用SAS 9.4软件进行统计学分析,利用多因素logistic回归分析血清铁蛋白与代谢综合征之间的关联。结果研究人群的代谢综合征标化患病率为39.04%。随着血清铁蛋白水平升高,代谢综合征患病率逐渐升高(P<0.05)。血清铁蛋白与WC、DBP、TG、FPG、hsCRP和HbA1c之间呈正相关,与HDL-C水平呈负相关(P<0.05)。多因素logistic回归分析结果显示,调整混杂因素后,女性血清铁蛋白与代谢综合征患病呈正相关(OR=3.59,95%CI:1.72~7.46)。结论武汉市江岸区居民代谢综合征患病率较高,血清铁蛋白与代谢综合征各组分指标相关,女性血清铁蛋白增高与代谢综合征高风险相关。Objective To explore the correlation between serum ferritin and the risk of metabolic syndrome,and to provide evidence for the prevention and control of metabolic syndrome.Methods Data was from the Jiang′an District survey data of the China Health and Nutrition Survey in 2022.A total of 399 adult residents were selected as the study subjects and the investigation was performed by questionnaire,physical examination and biochemical testing.Statistical analysis was conducted by SAS 9.4 software,and the association between serum ferritin and metabolic syndrome was analyzed by using multivariate logistic regression.Results The prevalence of metabolic syndrome in the study population was 39.04%after standrdization.With the increase of serum ferritin levels,the prevalence of metabolic syndrome gradually increased(P<0.05).Serum ferritin was positively correlated with WC,DBP,TG,FPG,hsCRP,and HbA1c,while negatively correlated with HDL-C(P<0.05).Multivariate logistic regression analysis showed that after adjusting for confounding factors,female serum ferritin was positively correlated with the prevalence of metabolic syndrome(OR=3.59,95%CI:1.72-7.46).Conclusion The prevalence of metabolic syndrome among residents in Jiang′an District is relatively high.Serum ferritin is associated with various components of metabolic syndrome,and the high serum ferritin level in women is associated with a higher risk of metabolic syndrome.

关 键 词：成年人 血清铁蛋白 代谢综合征 

分 类 号：R181[医药卫生—流行病学]