2003—2022年北京市朝阳区居民结直肠癌疾病负担及其变化趋势分析  

Analysis of disease burden and changing trend of colorectal cancer among residents in Chaoyang District of Beijing from 2003 to 2022

作　　者：宋娟[1] 孟海英[1] 黄立勇[1] 苏健婷[2] 齐啸[1] SONG Juan;MENG Haiying;HUANG Liyong;SU Jianting;QI Xiao(Department of Surveillance and Information,Beijing Chaoyang District Center for Disease Control and Prevention,Beijing 100021,China;Information and Statistics Center,Beijing Center for Disease Control and Prevention,Beijing 100013,China)

机构地区：[1]北京市朝阳区疾病预防控制中心监测信息科,北京100021 [2]北京市疾病预防控制中心信息统计中心,北京100013

出　　处：《职业与健康》2024年第24期3352-3356,3361,共6页Occupation and Health

基　　金：首都卫生发展科研专项(No.2018-1-1011)。

摘　　要：目的对2003—2022年北京市朝阳区户籍居民结直肠癌疾病负担及变化趋势进行分析,为制定适合朝阳区结直肠癌防控策略提供数据支持和科学依据。方法利用北京市卫生防病监测信息资源整合分析平台中的2003—2022年北京市朝阳区户籍居民死亡登记资料,分析结直肠癌的粗死亡率、标化死亡率、早死寿命损失年(years of life lost,YLL)、伤残寿命损失年(years of lived with disability,YLD)和伤残调整寿命年(disability-adjusted life years,DALY)及其平均年度变化百分比(average annual percent change,AAPC),采用Excel 2016、SPSS 17.0和Joinpoint软件4.6.0.0进行统计分析。结果2003—2022年,北京市朝阳区居民结直肠癌共死亡7764例,粗死亡率由10.78/10万上升至26.75/10万(AAPC=5.29%,P<0.01)。男性粗死亡率和标化死亡率、女性粗死亡率均呈上升趋势(AAPC=5.69%、0.97%、3.71%,均P<0.01);男性结直肠癌死亡人数、粗死亡率和标化死亡率均高于女性;男性和≥75岁女性死亡率均呈上升趋势(AAPC=3.07%、2.08%,均P<0.01)。45~<60岁男性死亡率呈上升趋势(AAPC=1.82%,P<0.05);结直肠癌YLL率、YLD率和DALY率均呈上升趋势(AAPC=3.71%、6.67%、3.80%,均P<0.01);男性YLL率、YLD率和DALY率及其上升速度均高于女性。45~<60和60~<75岁居民DALY在全年龄段中占比分别为21.96和40.76%。结论2003—2022年北京市朝阳区居民结直肠癌死亡率、标化死亡率和DALY率呈上升趋势,尤其是男性和老年人疾病负担日益严重。政府应对全人群进行健康教育,提倡健康的饮食习惯和生活方式,加大结直肠癌的早期筛查力度,尤其高危人群,做到早发现、早诊断、早治疗,降低结直肠癌的疾病负担。Objective To analyze the disease burden and change trend of colorectal cancer among registered residence residents in Chaoyang District of Beijing from 2003 to 2022,and to provide data support and scientific basis for formulating colorectal cancer prevention and control strategies suitable for Chaoyang District.Methods The death registration data of registered residence residents in Chaoyang District of Beijing from 2003 to 2022 were used to analyze the crude mortality,standardized mortality,years of life lost(YLL),years of lived with disability(YLD),disability-adjusted life years(DALY)and their average annual percent change(AAPC)of colorectal cancer in the integrated analysis platform of health and disease prevention monitoring information resources in Beijing.Excel 2016,SPSS 17.0 and Joinpoint Regression Program(version 4.6.0.0)were used for statistical analysis.Results From 2003 to 2022,there were a total of 7764 deaths from colorectal cancer among residents in Chaoyang District of Beijing,and the crude mortality increased from 10.78/100000 to 26.75/100000(AAPC=5.29%,P<0.01).The crude death rate,standardized death rate of male and crude death rate of female showed an increasing trend(AAPC=5.69%,0.97%,3.71%,all P<0.01).The number of deaths,crude mortality rate,and standardized mortality rate of colorectal cancer in male were higher than those in female.The mortality rate of both males and females age≥75 showed an upward trend(AAPC=3.07%,2.08%,all P<0.01).The mortality rate of males aged 45-<60 was is on the rise(AAPC=1.82%,P<0.05).The YLL rate,YLD rate and DALY rate of colorectal cancer showed an upward trend(AAPC=3.71%,6.67%,3.80%,all P<0.01).The YLL rate,YLD rate and DALY rate,and their rate of increase in males were higher than those in females.The proportion of DALY among residents aged 45-<60 and60-<75 in the entire age group was 21.96 and 40.76%,respectively.Conclusion The mortality rate,standardized mortality rate and DALY rate of colorectal cancer among residents in Chaoyang District of Beijing from 2

关 键 词：结直肠癌 死亡率 疾病负担 伤残调整寿命年 平均年度变化百分比 

分 类 号：R181.3[医药卫生—流行病学]