云南省人群乳腺癌生存率分析  

Analysis of breast cancer survival rate among population in Yunnan Province

作　　者：朱云芳 刘月 杨沧江[1] 文洪梅[1] 石青萍[1] 陈杨[1] ZHU Yunfang;LIU Yue;YANG Cangjiang;WEN Hongmei;SHI Qingping;CHEN Yang(Institute of Chronic Infectious Disease Prevention and Control,Yunnan Center for Disease Control and Prevention,Kunming,Yunnan 650022,China;Department of Public Health,Haiyuan College,Kunming Medical University,Kunming,Yunnan 650106,China)

机构地区：[1]云南省疾病预防控制中心慢性传染性疾病防制所,云南昆明650022 [2]昆明医科大学海源学院公共卫生系,云南昆明650106

出　　处：《职业与健康》2024年第24期3406-3410,共5页Occupation and Health

摘　　要：目的了解云南省乳腺癌生存现况,为恶性肿瘤防治提供参考依据。方法以云南省肿瘤登记地区1974—2022年收集的乳腺癌病例为研究对象,采用寿命表法和Kaplan-Maier法计算生存率,Cox回归进行多因素分析,并探究相关人口学和疾病状况特征对乳腺癌生存的影响。结果共纳入云南省36058例乳腺癌患者,患者年龄[M(P_(25),P_(75))]为51(44,59)岁,45~<55岁年龄组患者最多为12962例(37.50%),≥75岁年龄组发病人数最少为1797例(5.00%)。乳腺癌死亡7813例(21.70%),男性535例,女性7448例。中位生存期为256个月。1、3、5年生存率分别为85.00%、78.00%和73.00%,女性生存率为85.00%、78.00%和74.00%,总体高于男性,分别为68.00%、60.00%和57.00%。城市1、3、5年生存率分别为85.00%、78.00%和74.00%,农村分别为85.00%、78.00%和72.00%,生存率随着年龄别的升高而降低。结论2022年云南省乳腺癌生存率低于全国平均水平,云南省乳腺癌患者的生存情况虽有所提高,但与我国经济发达地区相比生存率仍较低。早发现早诊断早治疗是提高乳腺癌生存率的有效方法,需针对云南省的发病生存特点进一步加强乳腺癌防治工作。Objective To understand the survival status of breast cancer in Yunnan Province,provide a reference basis for the prevention and treatment of malignant tumors.Methods The breast cancer cases collected from 1974 to 2022 in the tumor registration area of Yunnan Province were used as the study population,the survival rates were calculated using the life table method and Kaplan-Maier method,the Cox regression was used for multifactor analysis,and the influence of relevant demographic and disease status characteristics on breast cancer survival was explored.Results A total of 36058 patients with breast cancer in Yunnan Province were included,the age of patients[M(P_(25),P_(75))]was 51(44,59)years old,the age group of 45-<55 years had the highest number of patients(12962 cases,37.50%),and the age group of≥75 years had the lowest number of patients(1797cases,5.00%).There were 7813(21.70%)deaths from breast cancer,535 in males and 7448 in females.The median survival time was 256 months.1,3 and 5 year survival rates were 85.00%,78.00%and 73.00%,respectively,with females having overall higher survival rates(85.00%,78.00%and 74.00%)than males(68.00%,60.00%and 57.00%).1,3 and 5 year survival rates in urban area were 85.00%,78.00%and 74.00%,respectively,while those in rural area were 85.00%,78.00%and 72.00%,respectively,and survival rate decreased with increasing age.Conclusions The survival rate of breast cancer in Yunnan Province in 2022 is lower than the national average.Although the survival of breast cancer patients in Yunnan Province has improved,the survival rate is still low compared with that in economically developed regions of China.The early detection,early diagnosis and early treatment is an effective method to improve the survival rate of breast cancer,and it is necessary to further strengthen the prevention and control of breast cancer according to the morbidity and survival characteristics of Yunnan Province.

关 键 词：云南省 乳腺癌 人群 生存率 生存分析 

分 类 号：R195.4[医药卫生—卫生统计学]