1,2,3-三氮唑及其衍生物的合成研究进展  

Research Progress on Synthesis of 1,2,3-Triazole and Its Derivatives

作　　者：臧曼淇 贾燕 李世慧 孙庆杰 高爱红 ZANG Manqi;JIA Yan;LI Shihui;SUN Qingjie;GAO Aihong(Sino-German Engineering College,Qingdao University of Science and Technology,Qingdao,Shandong,266000,China;Shandong Province Siwei Safety Production Technology Center,Jinan,Shandong,250014,China;Shandong Chemical Research Institute,Qingdao University of Science and Technology,Jinan,Shandong,250014,China)

机构地区：[1]青岛科技大学中德工程学院,山东青岛266000 [2]山东省思威安全生产技术中心,山东济南250014 [3]青岛科技大学山东化工研究院,山东济南250014

出　　处：《浙江化工》2025年第2期14-20,共7页Zhejiang Chemical Industry

基　　金：国家自然科学基金面上项目(52070089)。

摘　　要：综述了1,2,3-三氮唑及其衍生物的合成研究进展,特别关注了Huisgen反应、Sakai反应和Sharpless点击化学反应等关键合成方法,并对每种方法的优缺点进行分析,展望未来1,2,3-三氮唑衍生物合成的发展方向,提出对合成策略的优化和新方法的探索,以满足更广泛的应用需求。This paper reviews the research progress of the synthesis of 1,2,3-triazole and its derivatives,pays special attention to the key synthesis methods such as Huisgen reaction,Sakai reaction and sharpless click chemical reaction,analyzes the advantages and disadvantages of each method,looks forward to the future development direction of the synthesis of 1,2,3-triazole derivatives,and proposes the optimization of synthesis strategies and the exploration of new methods to meet the needs of a wider range of applications.

关 键 词：1 2 3-三氮唑 合成 Huisgen反应 Sakai反应 Sharpless点击化学反应 

分 类 号：TQ252[化学工程—有机化工]