前列腺癌内分泌治疗患者体重管理的最佳证据总结  

Best evidence summary of weight management in patients undergoing endocrine therapy for prostate cancer

作　　者：朱涵菁 郭艳[1] 殷弘凡 王贝贝 谢娟 杨艳[1] ZHU Hanjing;GUO Yan;YIN Hongfan;WANG Beibei;XIE Juan;YANG Yan(Department of Nursing,Renji Hospital,Shanghai Jiao Tong University School of Medicine,Shanghai 200127,China;Shanghai Jiao Tong University School of Nursing,Shanghai 200025,China)

机构地区：[1]上海交通大学医学院附属仁济医院护理部,上海200127 [2]上海交通大学护理学院,上海200025

出　　处：《上海交通大学学报(医学版)》2025年第2期194-203,共10页Journal of Shanghai Jiao tong University:Medical Science

基　　金：国家自然科学基金面上项目(72174120);上海市高水平地方高校创新团队(SHSMU-ZDCX20212800)。

摘　　要：目的·检索并评价前列腺癌患者在内分泌治疗过程中体重管理的相关证据,并总结最佳证据。方法·采用PIPOST模式构建循证问题。按照证据资源“6S”模型,使用计算机自上而下地系统检索国际指南协作网、BMJ最佳临床实践、UpToDate、JBI循证卫生保健中心数据库、美国指南网、医脉通、Cochrane Library、PubMed、CINAHL、Web of Science、Embase、中国知网、中国生物医学文献数据库、万方数据库、维普数据库,以及美国泌尿外科学会、欧洲泌尿外科学会、中华医学会泌尿外科分会网站中关于前列腺癌内分泌治疗过程中体重管理的相关证据,包括指南、临床决策、推荐实践、专家共识、证据总结、系统评价及原始研究。检索时限为建库至2023年12月。由2名研究人员独立对纳入文献进行质量评价。采用逐篇阅读的方式纳入文献,根据主题进行汇总。证据筛选及提取优先选择高等级、高质量、新发表的权威文献。纳入并提取的证据统一采用JBI证据预分级及证据推荐级别系统划分为1~5级,并将证据推荐建议划分为A级强推荐和B级弱推荐。结果·共检索到符合标准的文献12篇,其中指南4篇、专家共识3篇、证据总结2篇、随机对照试验2篇和类实验研究1篇。12篇文献均质量评价较高,全部纳入。最佳证据汇总归纳为体重管理评估及监测、多学科协作、个性化支持、家庭参与策略、营养管理策略、运动管理策略、健康教育和随访管理8个方面。结论·得到前列腺癌内分泌治疗过程中体重管理的最佳证据,归纳为8个方面;临床应用时,还需结合具体临床情况和患者特质,以提高临床干预效果及护理质量。Objective·To retrieve and evaluate evidence related to weight management during endocrine therapy for prostate cancer patients,and summarize the best evidence available.Methods·The PIPOST model was adopted to construct evidence-based questions.Following the“6S”model of evidence resources,a systematic computer-based search was conducted to retrieve relevant evidence on weight management during prostate cancer endocrine therapy from various databases and websites,including Guidelines International Network,BMJ Best Practice,UpToDate,JBI Evidence-Based Healthcare Center Database,American Guidelines Network,Medlive,Cochrane Library,PubMed,CINAHL,Web of Science,Embase,CNKI,Chinese Biomedical Literature Database,Wanfang Database,and VIP Database,as well as the websites of the American Urological Association,European Urological Association,and Urological Branch of Chinese Medical Association.The evidence retrieved included guidelines,clinical decisions,recommended practices,expert consensuses,evidence summaries,systematic reviews,and original studies.The search period spanned from database establishment to December 2023.Two researchers independently evaluated the quality of the included literature.The included articles were read one by one and summarized according to themes.Priority was given to high-level,high-quality,and newly published authoritative literature during evidence screening and extraction.The included and extracted evidence was uniformly classified into levels 1‒5 according to the JBI evidence pre-classification and evidence recommendation level system,and the evidence recommendations were divided into strongly recommended(Grade A)and weakly recommended(Grade B).Results·A total of 12 articles were retrieved,consisting of 4 guidelines,3 expert consensuses,2 evidence summaries,2 randomized controlled trials,and 1 quasi-experimental study.All 12 articles were rated as high quality and were included.The best evidence was summarized into 8 aspects:weight management assessment and monitoring,multidiscip

关 键 词：前列腺癌 内分泌治疗 体重管理 循证护理学 证据总结 

分 类 号：R473.73[医药卫生—护理学] R737.25[医药卫生—临床医学]