耳穴敷贴和夏枯草汤合海藻玉壶汤治疗良性甲状腺结节的效果  

Effect of Auricular Acupressure and Xiakucao Decoction Combined with Haizao Yuhu Decoction in the Treatment of Benign Thyroid Nodules

作　　者：陈明明 丁宇翃 江政烨 CHEN Mingming;DING Yuhong;JIANG Zhengye(Fuzhou Hospital of Traditional Chinese Medicine,Fujian University of Traditional Chinese Medicine,Fuzhou 350001,China;不详)

机构地区：[1]福建中医药大学附属福州中医院,福建福州350001 [2]福州市鼓楼区鼓东街道社区卫生服务中心

出　　处：《中外医学研究》2025年第5期13-17,共5页CHINESE AND FOREIGN MEDICAL RESEARCH

摘　　要：目的:分析耳穴敷贴和夏枯草汤合海藻玉壶汤治疗良性甲状腺结节(TN)的效果。方法:选取2022年1月—2023年12月福建中医药大学附属福州中医院内分泌科收治的93例良性TN患者作为研究对象,按随机数表法将其分为参照组(n=46,给予左甲状腺素钠片治疗)与中医组(n=47,在参照组基础上实施穴位敷贴和夏枯草汤合海藻玉壶汤治疗)。比较两组临床疗效、TN数目、TN直径、中医症候积分、血清指标[胰岛素生长因子-1(IGF-1)、转化生长因子-β(TGF-β)、血管内皮生长因子(VEGF)]。结果:中医组治疗总有效率为97.87%,明显高于参照组的78.26%,差异有统计学意义(P<0.05);中医组治疗后TN数目少于参照组,TN直径小于参照组,颈部触及结节、喉间梗阻感、善太息、情志抑郁、头晕目眩积分及IGF-1、VEGF水平低于参照组,TGF-β水平高于参照组,差异有统计学意义(P<0.05)。结论:良性TN患者实施耳穴敷贴和夏枯草汤合海藻玉壶汤治疗效果显著,可减少TN数目,缩小TN直径,改善临床症状与血清指标。Objective:To analyze the effect of auricular acupressure and Xiakucao Decoction combined with Haizao Yuhu Decoction in the treatment of benign thyroid nodules(TN).Method:A total of 93 benign TN patients in the Department of Endocrinology,Fuzhou Hospital of Traditional Chinese Medicine,Fujian University of Traditional Chinese Medicine from January 2022 to December 2023 were selected.According to the method of randomized number table,they were divided into reference group(n=46,given Levothyroxine Sodium Tablets treatment)and Chinese medicine group(n=47,given auricular acupressure and Xiakucao Decoction combined with Haizao Yuhu Decoction on the basis of the reference group).The total effective rate of treatment,TN number,TN diameter,traditional Chinese medicine symptom score,and the serum indexes[insulin growth factor-1(IGF-1),transforming growth factor-β(TGF-β),vascular endothelial growth factor(VEGF)levels]between the two groups were analyzed.Result:The total effective rate of treatment in the Chinese medicine group was 97.87%,which was significantly higher than 78.26%of in the reference group,the differences were statistically significant(P<0.05).After treatment,the TN number in the Chinese medicine group was less than that in the reference group,the TN diameter was significantly smaller than that in the reference group,the scores of number of touching nodules in the neck,feeling of obstruction between the larynx,sighing respiration,depression,dizziness and vertigo,the levels of IGF-1 and VEGF in the Chinese medicine group were significantly lower than those in the reference group,and the level of TGF-βwas significantly higher than that in the reference group,the differences were statistically significant(P<0.05).Conclusion:The implementation of auricular acupressure and Xiakucao Decoction combined with Haizao Yuhu Decoction in patients with benign TN has significant therapeutic effects,which can reduce the number of TN,shrink the diameter of TN,improve clinical symptoms and serum indexes.

关 键 词：耳穴敷贴 夏枯草汤 海藻玉壶汤 良性甲状腺结节 

分 类 号：R259[医药卫生—中西医结合]