基于环形芯PCF检测的BRCA浓度和温度双参量传感结构  

Dual-parameter sensing structure for BRCA concentration and temperature based on ring-core PCF detection

作　　者：程曦 施伟华[1] 范雨艳 顾钰颖 CHENG Xi;SHI Weihua;FAN Yuyan;GU Yuying(College of Electronic and Optical Engineering&College of Flexible Electronics(Future Technology),Nanjing University of Posts&Telecommunications,Nanjing 210023,China)

机构地区：[1]南京邮电大学电子与光学工程学院、柔性电子(未来技术)学院,南京210023

出　　处：《光通信技术》2025年第1期88-93,共6页Optical Communication Technology

基　　金：国家自然科学基金项目(61571237)资助;江苏省自然科学基金项目(20221330)资助;江苏省研究生科研创新计划项目(SJCX22_0258)资助。

摘　　要：为了避免温度波动对生物参数的影响,提出了一种基于环形芯光子晶体光纤(PCF)检测的乳腺癌易感基因(BRCA)浓度和温度的多参数传感结构。该结构在外表面涂覆了一层金膜,创建了表面等离子共振传感通道,专门用于检测BRCA浓度;同时,在PCF中心的空气孔中填充了一种温敏液体,构建了定向耦合传感通道,用于精确检测温度,从而能够校正温度变化对BRCA浓度测量可能产生的影响。仿真结果表明:传感结构的浓度和温度2个传感通道各自独立工作,在BRCA浓度为0~7.69 mM时,浓度灵敏度可达19.5 nm/mM;而在温度为20~40℃时,温度灵敏度为-6.4 nm/℃。To mitigate the influence of temperature fluctuations on biological parameters,this paper proposes a multi-parameter sensing structure based on ring-core photonic crystal fiber(PCF)detection for measuring both the concentration of the breast cancer susceptibility gene(BRCA)and temperature.The proposed structure features an outer surface coated with a gold film,which creates a surface plasmon resonance sensing channel specifically designed for detecting BRCA concentration.Simultaneously,a thermosensitive liquid is filled into the central air holes of the PCF,forming a directional coupling sensing channel dedicated to precise temperature measurement.This design enables the correction of potential impacts of temperature changes on BRCA concentration measurements.The simulation results indicate that the concentration and temperature sensing channels of the sensor structure operate independently.Specifically,for the concentration sensing channel,when the BRCA concentration ranges from 0 to 7.69 mM,the concentration sensitivity can reach 19.5 nm/mM.For the temperature sensing channel,within a temperature range of 20 to 40℃,the temperature sensitivity is-6.4 nm/℃.

关 键 词：光子晶体光纤 表面等离子体共振 定向耦合 生物传感 温度传感 

分 类 号：TN929.1[电子电信—通信与信息系统]