临床药师参与109例血栓抗凝用药会诊及典型案例分析  

Consultation and Typical Case Analysis of 109 Cases of Thrombotic Anticoagulant Drugs Participated by Clinical Pharmacists

作　　者：罗见春 李秀英 万英 钟川 蒋欣星 LUO Jianchun;LI Xiuying;WAN Ying;ZHONG Chuan;JIANG Xinxing(Dept.of Pharmacy,the Affiliated Hospital of Southwest Medical University,Sichuan Luzhou 646099,China;School of Basic Medical Sciences,Southwest Medical University,Sichuan Luzhou 646099,China;Dept.of Neurology,People’s Hospital of Chonqing Dazu District,Chongqing 402360,China;Dept.of Medical Affairs,People’s Hospital of Chonqing Dazu District,Chongqing 402360,China)

机构地区：[1]西南医科大学附属医院药学部,四川泸州646099 [2]西南医科大学基础医学院,四川泸州646099 [3]重庆市大足区人民医院神经内科,重庆402360 [4]重庆市大足区人民医院医务部,重庆402360

出　　处：《中国医院用药评价与分析》2025年第2期227-229,234,共4页Evaluation and Analysis of Drug-use in Hospitals of China

基　　金：国家自然科学基金资助项目(No.82071319);重庆市大足区科学技术局资助项目(No.DZKJ2022JSYJ-KWXM1014)。

摘　　要：目的:通过对临床真实病例的回顾性分组比较,探讨临床药师参与血栓抗凝用药会诊的效果。方法:收集2023年西南医科大学附属医院临床药师参与的109例血栓抗凝用药会诊的住院患者病例资料,通过临床医师是否采纳药师抗凝用药建议分为采纳组(86例)与非采纳组(23例),比较两组患者的性别、年龄、主要入院诊断、血栓防治的总有效率、凝血功能指标等指标。结果:采纳组患者血栓消退、血栓部分消退和血栓未见进展情况,D-二聚体、纤维蛋白降解产物水平降低情况均优于非采纳组,且采纳组患者的出血发生率仅为6.98%(6例)。结论:临床药师参与血栓抗凝用药会诊,有助于提高治疗效果,体现了临床药师的价值。OBJECTIVE:To probe into the effects of clinical pharmacists participating into the consultation of thrombotic anticoagulant drugs by retrospective grouping of clinical real cases.METHODS:Clinical data of 109 inpatients with consultation of thrombotic anticoagulant drugs participated by clinical pharmacists in the Affiliated Hospital of Southwest Medical University in 2023 were collected.According to whether the clinicians adopted the anticoagulant drugs recommendations by pharmacists,all patients were divided into the adoption group(86 cases)and the non-adoption group(23 cases).The gender,age,main admission diagnosis,total effective rate of thrombosis prevention and treatment,coagulation function indicators of two groups were compared.RESULTS:Compared with the non-adoption group,patients in the adoption group had better thrombus resolution,partial thrombus resolution and no progression of thrombus,decreased D-dimer and fibrin degradation products indicators,and the incidence of bleeding in the adoption group was only 6.98%(6 cases).CONCLUSIONS:The participation of clinical pharmacists in the consultation process of thrombus anticoagulant drugs can help to improve the treatment effectiveness and reflect the value of clinical pharmacists.

关 键 词：血栓抗凝用药会诊 临床药师 案例分析 

分 类 号：R973.2[医药卫生—药品]