Association of a modified uterine manipulation method with improved recovery after laparoscopic radical hysterectomy:a retrospective cohort study  

作　　者：Yu-Shu Sun Ling-Jie Bao Yin-Ping Xiao Kai-Kai Chang Yan Du Xiao-Fang Yi 

机构地区：[1]Department of Gynecology,Obstetrics and Gynecology Hospital,Fudan University,Shanghai 200011,China [2]Department of Obstetrics and Gynecology of Shanghai Medical School,Fudan University,Shanghai 200011,China [3]Shanghai Key Laboratory of Female Reproductive Endocrine Related Diseases,Shanghai 200011,China [4]Department of Pathology,Obstetrics and Gynecology Hospital,Fudan University,Shanghai 200011,China.

出　　处：《Reproductive and Developmental Medicine》2024年第4期213-219,共7页生殖与发育医学(英文版)

基　　金：Clinical Research Foundation of Shanghai Municipal Health Commission(20214Y0218);Key Technologies Research and Development Program(2022YFC2704000);Shanghai Clinical Research Center for Gynecological Diseases(22MC1940200)。

摘　　要：Objective:Uterine manipulation with an intrauterine device is the surgical method used for early-stage cervical cancer.In this study,we explored a modified uterine manipulation method without the using an intrauterine device during laparoscopic radical hysterectomy(LRH)of patients with early-stage cervical cancer.Methods:We retrospectively collected data of patients with early-stage cervical cancer who underwent LRH between January 2015 and June 2019.The clinicopathological characteristics and surgical outcomes of patients treated with the new method(Group S)were compared to those of patients treated with the conventional uterine manipulator(Group M).Results:A total of 100 patients were included in the study,with 54 patients in Group M and 46 patients in Group S.No significant difference was observed in clinicopathological characteristics between the two groups.Compared to Group M,Group S had a significantly shorter duration of postoperative fever(0vs.3 days,P=0.003)and a shorter duration of secondary antibiotic use(4vs.5 days,P=0.035).Additionally,the cost of antibiotics was lower in Group S($95.45vs.$135.22,P=0.032).The modified uterine manipulation method was associated with a lower risk of postoperative fever(P=0.007).No difference was found in the 2-year disease-free survival(P=0.409)and 2-year overall survival between the two groups(P=0.718).Conclusions:The modified uterine suture suspension method is easy to perform,enhances postoperative recovery,and could be a viable option for patients with early-stage cervical cancer.

关 键 词：Early-stage cervical cancer Minimally invasive surgery Uterine suspension Uterine manipulator PROGNOSIS 

分 类 号：R73[医药卫生—肿瘤]