复合酸联合消痤汤治疗轻中度痤疮的临床疗效分析  

Clinical Efficacy of Compound Acid Combined with Xiaocuo Decoction in the Treatment of Mild to Moderate Acne

作　　者：张肖平 朱秀丽 黄连明 陈韦佟 ZHANG Xiaoping;ZHU Xiuli;HUANG Lianming;CHEN Weitong(Department of Dermatology,Yantai Academy of Agricultural Sciences Traditional Chinese Medicine Dermatology Hospital,Yantai 265500,Shandong,China)

机构地区：[1]烟台市农科院中医皮肤病医院皮肤科,山东烟台265500

出　　处：《中国美容医学》2025年第3期120-123,共4页Chinese Journal of Aesthetic Medicine

摘　　要：目的:分析复合酸联合消痤汤治疗轻中度痤疮的临床疗效,为其临床应用提供科学依据。方法:选取2021年7月-2023年7月在笔者医院皮肤科就诊的轻中度痤疮患者共60例,给予德菲林复合酸+消痤汤治疗,疗程为8周。观察治疗总有效率、治疗前后痤疮综合分级系统GAGS评分(Global acne grading system,GAGS)变化以及痤疮特异性生活质量量表Acne-QoL评分(Acne-specific quality of life questionnaire,Acne-QoL)变化情况,并记录治疗期间不良反应情况。结果:治疗总有效率为75%;治疗后,GAGS评分(6.57±1.69)分,低于治疗前的(18.67±5.28)分;Acne-QoL评分(25.13±1.82)分,高于治疗前的(12.97±3.40)分,差异均有统计学意义(P<0.05);治疗期间出现恶心1例,瘙痒1例,不良反应的出现概率为3.33%。结论:复合酸联合消痤汤可有效治疗轻中度痤疮,且具有较好的安全性,值得临床推广应用。Objective To evaluate the clinical efficacy of compound acid combined with Xiaocuo Decoction in the treatment of mild to moderate acne and to provide scientific evidence for its clinical application.Methods A total of 60 patients with mild to moderate acne who visited the Department of Dermatology at our hospital between July 2021 and July 2023 were included in the study.These patients were treated with compound acid in combination with Xiaocuo Decoction for a duration of 8 weeks.The overall response rate was recorded,and the GAGS score and Acne-QoL score were compared before and after treatment.The incidence of adverse reactions during treatment was also documented.Results The overall response rate was 75%.The GAGS score after treatment (6.57±1.69) was significantly lower than before treatment (18.67±5.28).The Acne-QoL score after treatment (25.13±1.82) was significantly higher than before treatment (12.97±3.40),with both differences being statistically significant (P<0.05).During the treatment,one patient experienced nausea,and another experienced itching,with an adverse reaction rate of 3.33%.Conclusion Compound acid combined with Xiaocuo Decoction effectively treats mild to moderate acne and demonstrates good safety.This therapeutic approach is worthy of wider clinical application.

关 键 词：复合酸 消痤汤 痤疮 临床疗效 

分 类 号：R758.733[医药卫生—皮肤病学与性病学]