Tissue fluidity:biophysical shape-shifting for regeneration  

作　　者：Zitong C Zhenyu C Y.Rinkevich 

机构地区：[1]Institute of Regenerative Biology and Medicine,Chinese Institutes for Medical Research,Fangtai District,Beijing 100069,China [2]Capital Medical University,Fengtai District,Beijing 100054,China

出　　处：《Signal Transduction and Targeted Therapy》2024年第12期5375-5376,共2页信号转导与靶向治疗(英文)

基　　金：supported by grants from the Institute of Regenerative Biology and Medicine,Chinese Institutes for Medical Research,and Capital Medical University.Figure 1 was created using BioRender.

摘　　要：In a recent study published in Cell,Sarate et al.developed a novel mouse epidermal injury model through genetic ablation of basal epidermal cells,revealing a physical transition of epidermal cells from solid to fluid-like states.Through combined omics approaches,they discovered that tissue fluidization is regulated by the EGFR/MEK/AP1 signaling axis,opening new opportunities to reactivate stem cells for wound repair1(Fig.1).

关 键 词：WOUND FLUIDITY 

分 类 号：Q247[生物学—细胞生物学]