玻璃体腔注射药物的药学服务专家共识  

Expert consensus on pharmaceutical care for drugs administered by intravitreal injection

作　　者：无 王家伟 宋智慧[5] 

机构地区：[1]北京药盾公益基金会眼科药学专业委员会 [2]中国药师协会药物治疗管理工作委员会 [3]中国医疗保健国际交流促进会临床药学分会. [4]不详 [5]首都医科大学附属北京同仁医院药学部

出　　处：《药物不良反应杂志》2025年第2期65-78,共14页Adverse Drug Reactions Journal

摘　　要：玻璃体腔注射(IVI)是利用注射器将药物运送至玻璃体腔的给药技术,目前已有多个IVI药物相继获批用于治疗眼底疾病,包括抗血管内皮生长因子类药物、眼内缓释糖皮质激素类药物等,同时,也存在多种超说明书用于IVI的药物。目前尚缺乏针对IVI药物临床应用的药学服务指导文件。为推动IVI药物药学服务工作的开展,北京药盾公益基金会眼科药学专业委员会,中国药师协会药物治疗管理工作委员会,中国医疗保健国际交流促进会临床药学分会组织专家根据临床实践经验,参考国内外相关研究数据、指南及文献等,制定本共识。本共识对临床应用IVI药物的特点,注射前、注射中及注射后的相关药学服务等内容进行梳理,对5个临床问题形成26条推荐意见,供各级医疗机构开展IVI药物药学服务时使用。使用者为各级医疗机构的医务人员(包括药师、医师、护士等相关工作人员),药事服务目标人群主要是应用IVI药物的患者。Intravitreal injection(IVI)is an administration technique that uses a syringe to deliver drugs into the vitreous cavity.Currently,multiple IVI drugs have been successively approved for the treatment of various fundus diseases,including antivascular endothelial growth factor drugs,intravitreal sustained-release glucocorticoid drugs,and so on.Meanwhile,there are many injection drugs off label used by IVI.At present,there is a lack of pharmaceutical care guidance documents for the clinical application of IVI drugs.To promote the development of pharmaceutical care for IVI drugs,Ophthalmic Pharmacy Professional Committee of Peking Safety Medicine Foundation,Medicine Therapy Management Working Committee of Chinese Pharmacists Association,and Clinical Pharmacy Branch of China International Exchange and Promotive Association for Medical and Health Care organized experts to formulate this consensus based on clinical practice experience and with reference to relevant domestic and foreign research data,guidelines,and literature.This consensus combs the characteristics of clinical application of IVI drugs,relevant pharmaceutical services before,during and after injection,and forms 26 recommendations for 5 clinical issues,which can be used by medical institutions at all levels to carry out pharmaceutical services of IVI drugs.The users are medical staff in medical institutions at all levels(including pharmacists,physicians,nurses,and other relevant staff),and the target population for application is mainly patients using IVI drugs.

关 键 词：眼科学 玻璃体腔注射 药学服务 专家共识 

分 类 号：R95[医药卫生—药学]