异荭草素的药理学作用研究进展  

Research Progress on Pharmacological Effects of Isoorientin

作　　者：潘晓瑜[1] 朱俊访[1] 韩晋辉[1] 罗燕娜[1] 肖迪虎 PAN Xiao-yu;ZHU Jun-fang;HAN Jin-hun;LUO Yan-na;XIAO Di-hu(Guang Dong Food and Drug Vocational College,Guangzhou,Guangdong,512000,China)

机构地区：[1]广东食品药品职业学院,广东广州512000

出　　处：《现代生物医学进展》2025年第1期193-200,共8页Progress in Modern Biomedicine

基　　金：广东省中医药局科研项目(20232117)。

摘　　要：异荭草素广泛存在于多种植物中,是一种木犀草素糖苷类天然黄酮物质,如淡竹叶、满天星、龙胆草、鸭拓草、西番莲、葫芦果、玉米、黑米、荞麦、山楂、黄瓜等,分子式是C_(21)H_(20)O_(11),分子量448.38。现已发现异荭草素具有抗氧化、抗炎、抗菌、降糖、降脂以及肝损伤保护等多种生物学功能,并且具有治疗包括肿瘤在内的多种疾病的潜力。在调节多种代谢性疾病方面具有显著效果,特别是在改善高血糖、高脂血症以及胰岛素抵抗等并发症方面显示出强大的潜力。为了更好地了解这种黄酮在改善人类健康方面的治疗潜力,该文就近年来异荭草素药理活性的研究进展作一综述,以期为食源性植物化学成分用于疾病预防和治疗提供新思路,也为异红草素的进一步开发应用提供理论依据。Isoorientin,a natural flavonoid of luteolin glycosides,exists in many kinds of plants and foods,such as pale bamboo leaves,starry sky,gentian grass,duckweed,passion fruit,gourd fruit,corn,black rice,buck-wheat,hawthorn and cucumber.The molecular formula is C_(21)H_(20)O_(11),with a molecular weight of 448.38.It has multi-ple biological functions such as antioxidant,anti-inflammatory,antibacterial,hypoglycemic,lipid-lowering,and liver injury protection,and so on.It has the potential to treat a variety of diseases,including cancer.It has significant effects in regulating various metabolic diseases,especially showing strong potential in improving complications such as hyperglycemia,hyperlipidemia,and insulin resistance.In order to better understand the therapeutic potential of this flavonoid in improving human health,this paper invstiagte many researches on the pharmacological activity of Isoorientin in recent years,aiming to provide new ideas for the use of food derived phytochemicals in disease pre-vention and treatment,as well as theoretical basis for the further development and application of isoorientin.

关 键 词：异荭草素 药理作用 疾病治疗 研究进展 

分 类 号：R3[医药卫生—基础医学] R961.1