头孢呋辛防治骨科手术患者感染的效果探究  

Study on the Curative Effect of Cefuroxime on Prevention and Treatment of Infection in Patients Undergoing Orthopedic Surgery

作　　者：黄小昆 路来成 王芳 HUANG Xiaokun;LU Laicheng;WANG Fang(Department of Pharmacy,Shanghe Traditional Chinese Medicine Hospital,Jinan 250000,China;Department of Surgery3rd,Shanghe Traditional Chinese Medicine Hospital,Jinan 250000,China;Pharmacy of Western Medicine,Shanghe Traditional Chinese Medicine Hospital,Jinan 250000,China)

机构地区：[1]山东省商河县中医医院药剂科,山东济南250000 [2]山东省商河县中医医院外三科,山东济南250000 [3]山东省商河县中医医院西药房,山东济南250000

出　　处：《中国伤残医学》2024年第23期73-76,共4页Chinese Journal of Trauma and Disability Medicine

摘　　要：目的:探讨骨科手术患者使用头孢呋辛防治感染的效果。方法:回顾性分析2022年1月—2023年5月商河县中医医院收治的108例骨科手术患者资料,根据头孢呋辛使用时机的不同,将其分为研究组及对照组,各54例。研究组术前0.5~1.0h内合理使用足量头孢呋辛滴注,术后12h继续足量头孢呋辛治疗;对照组术后进行头孢呋辛静脉滴注。观察对比两组患者的术后愈合情况、术后感染情况及术后平均住院时间。结果:研究组的甲级愈合率为87.04%,高于对照组的57.41%,差异有统计学意义(P<0.05)。研究组的术后感染率为1.85%,低于对照组的14.81%,差异有统计学意义(P<0.05)。研究组的住院时间短于对照组,差异有统计学意义(P<0.05)。结论:骨科手术患者根据具体情况合理应用头孢呋辛,可促进术后愈合,降低术后感染率,缩短患者住院时间,具有一定的应用价值。Objective:To investigate the effect of cefuroxime on prevention and treatment of infection in Patients with orthopedic surgery.Methods:The data of 108 orthopedic surgery patients admitted to Shanghe Traditional Chinese Medicine Hospital from January 2022 to May 2023 were retrospectively analyzed.According to the different use times of cefuroxime,they were divided into a study group and a control group,with 54 cases each.In the study group,adequate cefuroxime was administered reasonably within 0.5 to 1.0 h before surgery,and adequate cefuroxime was continued 12 h after surgery.In the control group,cefuroxime was given intravenously after surgery.The postoperative healing,postoperative infection and average postoperative hospital stay of the two groups were observed and compared.Results:The Grade A healing rate of the study group was 87.04%,which was higher than 57.41%of the control group,the difference was statistically significant(P<0.05).The postoperative infection rate of the study group was 1.85%was,lower than 14.81%of the control group,and the difference was statistically significant(P<0.05).The length of hospitalization in the study group was shorter than that in the control group,and the difference was statistically significant(P<0.05).Conclusion:Reasonable application of cefuroxime in orthopedic surgery patients according to specific conditions can promote postoperative healing,reduce postoperative infection rate and shorten hospital stay of patients,which has certain application value.

关 键 词：骨科手术 头孢呋辛 术后愈合 术后感染 住院时间 

分 类 号：R687.3[医药卫生—骨科学]