玉屏风散联合穴位贴敷治疗小儿喘息性支气管肺炎肺功能损伤的效果研究  

Effect of Yupingfeng Powder Combined with Acupoint Application on Pulmonary Function Injury of Children with Asthmatic Bronchopneumonia

作　　者：杨建美 YANG Jianmei(Department of Pediatrics No.1,Heze Hospital of Traditional Chinese Medicine,Heze 274000,China)

机构地区：[1]山东省菏泽市中医医院儿一科,山东菏泽274000

出　　处：《中国伤残医学》2024年第23期90-94,共5页Chinese Journal of Trauma and Disability Medicine

基　　金：2020年度山东省中医药科技项目任务(2020M202)。

摘　　要：目的:探究小儿喘息性支气管肺炎肺功能损伤患儿予以玉屏风散、穴位贴敷联合治疗的临床效果。方法:选取2022年10月—2024年8月菏泽市中医医院收治的60例喘息性支气管肺炎肺功能损伤患儿为研究对象,按随机数字表法将其分为对照组和研究组,各30例。对照组予以常规西医治疗,研究组在对照组基础上采用玉屏风散联合穴位贴敷治疗。两组均治疗7d。对比两组临床疗效、症状体征消失时间、炎性因子水平、免疫功能指标、不良反应发生情况。结果:研究组治疗总有效率为93.33%,高于对照组的73.33%,差异有统计学意义(P<0.05)。研究组退热时间为(1.72±0.25)d、喘息消失时间为(4.20±0.33)d、止咳时间为(2.54±0.29)d、肺部啰音消失时间为(4.12±0.39)d,均短于对照组的(2.81±0.43)d、(6.35±0.42)d、(4.41±0.38)d、(6.20±0.55)d,差异均有统计学意义(P<0.05)。治疗后,研究组肿瘤坏死因子-α为(3.10±0.48)μg/L、白细胞介素(IL)-10为(3.06±0.32)μg/L、IL-6为(3.66±0.75)μg/L、C反应蛋白为(6.82±0.53)mg/L,均低于对照组的(4.82±0.70)μg/L、(3.53±0.38)μg/L、(4.93±1.29)μg/L、(10.34±0.76)mg/L;免疫球蛋白(Ig)A为(1.23±0.31)g/L、IgG为(12.16±2.53)g/L、IgM为(2.10±0.52)g/L,均高于对照组的(0.98±0.25)g/L、(9.83±2.01)g/L、(1.79±0.45)g/L,差异均有统计学意义(P<0.05)。两组不良反应发生率分别为16.67%、23.33,两组对比,差异无统计学意义(P>0.05)。结论:喘息性支气管肺炎肺功能损伤患儿采用玉屏风散联合穴位贴敷治疗的效果较好,能够有效降低患儿炎症反应,促进免疫功能改善,有助于临床症状消退,具有一定的安全性。Objective:To explore the clinical effect of Yupingfeng Powder and acupoint application in the treatment of pulmonary function injury of children with asthmatic bronchopneumonia.Methods:A total of 60 children with asthmatic bronchopneumonia with pulmonary function injury admitted to Heze Hospital of Traditional Chinese Medicine from October 2022 to August 2024 were selected as the research objects,and were divided into a control group and a study group according to random number table method,with 30 cases in each group.The control group was treated with conventional Western medicine,and the study group was treated with Yupingfeng Powder combined with acupoint application on the basis of the control group.Both groups were treated for 7 days.The clinical efficacy,disappearance time of symptoms and signs,levels of inflammatory factors,immune function indexes and occurrence of adverse reactions were compared between the two groups.Results:The total effective rate of the study group was 93.33%,which was higher than 73.33%of the control group,the difference was statistically significant(P<0.05).In the study group,the time of fever reduction was(1.72±0.25)d,the time of wheezing disappearance was(4.20±0.33)d,the time of cough relief was(2.54±0.29)d,and the time of lung rale disappearance was(4.12±0.39)d,which were shorter than(2.81±0.43)d,(6.35±0.42)d,(4.41±0.38)d and(6.20±0.55)d in the control group,and the differences were statistically significant(P<0.05).After treatment,tumor necrosis factor-αwas(3.10±0.48)μg/L,interleukin(IL)-10 was(3.06±0.32)μg/L,IL-6 was(3.66±0.75)μg/L,C-reactive protein was(6.82±0.53)mg/L,which were lower than(4.82±0.70)μg/L,(3.53±0.38)μg/L,(4.93±1.29)μg/L,(10.34±0.76)mg/L in control group;The immunoglobulin(Ig)A,IgG and IgM were(1.23±0.31)g/L,(12.16±2.53)g/L,and(2.10±0.52)g/L,all of which were higher than(0.98±0.25)g/L,(9.83±2.01)g/L,and(1.79±0.45)g/L of the control group,the differences were statistically significant(P<0.05).The incidence of adverse reactions in the

关 键 词：小儿喘息性支气管肺炎 肺功能损伤 玉屏风散 穴位贴敷 症状体征 炎性因子 免疫功能 

分 类 号：R725.6[医药卫生—儿科]