基于血流储备分数指导的经皮冠脉介入术治疗对冠状动脉多支病变患者相关指标及预后的影响  

Effect of Percutaneous Coronary Intervention Guided by Flow Reserve Fraction on Related Indexes and Prognosis of Patients with Multi-Vessel Coronary Artery Disease

作　　者：黄文镇 廖秀梅 陈雅婷 陈玉双[1] 刘敬山[1] 吴家慧 HUANG Wen-zhen;LIAO Xiu-mei;CHEN Ya-ting;CHEN Yu-shuang;LIU Jing-shan;WU Jia-hui(Catheter Room of Zhangzhou Hospital,Fujian Province,Fujian Zhangzhou 363000;Pharmacy of Zhangzhou Fourth Hospital,Fujian Zhangzhou 363000)

机构地区：[1]福建省漳州市医院导管室,福建漳州363000 [2]漳州市第四医院药房,福建漳州363000

出　　处：《中国医疗器械信息》2025年第3期136-139,共4页China Medical Device Information

摘　　要：目的:探究基于血流储备分数(FFR)指导的经皮冠脉介入术(PCI)治疗冠状动脉多支病变患者的临床效果。方法:回顾性分析2022年6月~2023年10月福建省漳州市医院收治的135例冠状动脉多支病变患者临床资料,按照治疗方法不同分为两组,将冠脉造影检查下行PCI治疗的67例设为对照组,将FFR指导下PCI治疗的68例设为观察组。比较两组PCI相关指标、心功能指标、心肌损伤标志物、预后情况。结果:观察组支架置入数、造影剂用量少于对照组(P<0.05);观察组术后心功能优于对照组,术后心肌损伤标志物较对照组低,预后不良心血管事件发生率低于对照组,有统计学差异(P<0.05)。结论:基于FFR指导的PCI治疗冠状动脉多支病变效果更佳,可减少支架置入数量,更好改善心功能,且后续不良心血管事件风险低。Objective:To explore the clinical effect of percutaneous coronary intervention(PCI)guided by flow reserve fraction(FFR)in patients with multi-vessel coronary artery disease.Methods:The clinical data of 135 patients with multi-vessel coronary artery disease treated in Zhangzhou Hospital of Fujian Province from June 2022 to October 2023 were retrospectively analyzed,and they were divided into two groups according to different treatment methods.67 cases receiving PCI under coronary angiography were set as control group,and 68 cases receiving PCI under FFR guidance were set as observation group.PCI related indexes,cardiac function indexes,myocardial injury markers and prognosis were compared between the two groups.Results:The number of stent placement and contrast agent dosage in observation group were less than those in control group(P<0.05).The postoperative cardiac function of the observation group was better than that of the control group,the level of postoperative myocardial injury markers was lower than that of the control group,and the incidence of adverse prognostic cardiovascular events was lower than that of the control group,with statistical difference(P<0.05).Conclusion:PCI guided by FFR is more effective in the treatment of multi-vessel coronary artery disease,which can reduce the number of stent implantation,better improve cardiac function,and lower the risk of subsequent adverse cardiovascular events.

关 键 词：冠状动脉多支病变 血流储备分数 经皮冠脉介入术 预后 

分 类 号：R445[医药卫生—影像医学与核医学]