补充维生素D结合悬吊式腰腹肌训练对OVCF术后患者康复效果及骨代谢指标的影响  

Effects of vitamin D supplementation combined with suspended lumbar and abdominal muscle training on rehabilitation and bone metabolism indexes in patients with OVCF after surgery

作　　者：王广健 孙绍玲 孙绍伟 蒋维慧 刘玉斌 Wang Guangjian;Sun Shaoling;Sun Shaowei;Jiang Weihui;Liu Yubin(Department of Rehabilitation Medicine,Yantaishan Hospital,Yantai 264000,China;Orthopedics Department,Yantaishan Hospital South District,Yantai 264000,China;Children Rehabilitation 6th Department,Linyi City Fehabilitation Hospital,Linyi 276000,China)

机构地区：[1]烟台市烟台山医院康复医学科,烟台264000 [2]烟台市烟台山医院南院骨科,烟台264000 [3]临沂市康复医院儿童康复六科,临沂276000

出　　处：《中华内分泌外科杂志(中英文)》2025年第1期101-105,共5页Chinese Journal of Endocrine Surgery

基　　金：烟台市科技创新发展计划基础研究类项目(2023JCYJ071)。

摘　　要：目的:探究补充维生素D结合悬吊式腰腹肌训练对骨质疏松性椎体压缩骨折(OVCF)术后患者康复效果及骨代谢指标的影响。方法:收集2021年6月至2024年6月在烟台山医院就诊的140例OVCF患者为研究对象,以随机数字表法分为对照组和观察组,各70例,分别采用悬吊式腰腹肌训练治疗和补充维生素D结合悬吊式腰腹肌训练治疗。评估两组康复效果即VAS、Oswestry功能障碍指数(ODI)评分及Cobb角、腰腹肌肌力、25-羟基维生素D[25(OH)D]、骨密度T值、骨代谢指标水平[血清骨钙素(OC)、降钙素(CT)、总Ⅰ型胶原氨基端延长肽(tPINP)、Ⅰ型胶原羧基端肽β特殊序列(β-CTX)、全段甲状旁激素(iPTH),骨碱性磷酸酶(BALP)]。结果:相较对照组,观察组治疗后VAS、ODI评分更低(t=13.66,t=9.87,P<0.05);相较对照组,观察组治疗后腰肌力评分、25(OH)D水平、骨密度T值更高(t=57.63,t=6.64,t=5.01,P<0.05),Cobb角更小(t=9.21,P<0.05);相较对照组,观察组治疗后骨代谢指标OC、CT、BALP、tPINP更高(t=4.21,t=3.05,t=2.66,t=3.16,P<0.05)、iPTH、β-CTX更低(t=7.28,t=3.50,P<0.05)。结论:补充维生素D联合悬吊式腰腹肌训练会促进OVCF患者术后的康复效果,改善患者术后的骨代谢指标水平。Objective:To explore the effects of vitamin D supplementation combined with suspended lumbar abdominal muscle training on rehabilitation and bone metabolism indexes of patients after OVCF.Methods:A total of 140 patients with osteoporotic vertebral compression fractures(OVCF)treated at Yantaishan Hospital from Jun.2021 to Jun.2024 were included in this study.Patients were randomly assigned to a control group and an observation group using a random number table,with 70 patients in each group.The control group received suspension lumbar and abdominal muscle training,while the observation group received vitamin D supplementation combined with suspension lumbar and abdominal muscle training.Outcomes evaluated included VAS scores,Oswestry Disability Index(ODI),Cobb Angle,lumboabdominal muscle strength,and serum levels of 25-hydroxyvitamin D[25(OH)D],bone mineral density T value,and bone metabolism markers[serum osteocalcin(OC),calcitonin(CT),total type I collagen amino-terminal propeptide(tPINP),type I collagen carboxy-terminal peptideβspecial sequence(β-CTX),intact parathyroid hormone(iPTH),and bone-specific alkaline phosphatase(BALP)]measured by chemiluminescence.Results:In comparison with the control group,the VAS and ODI scores in the observation group were lower after treatment(t=13.66,t=9.87,P<0.05).Compared to the control group,the lumbar muscle strength score of the observation group,the 25(OH)D level and bone mineral density T value was higher after treatment(t=57.63,t=6.64,t=5.01,P<0.05),and the Cobb Angle was smaller(t=9.21,P<0.05).Compared with the control group,the bone metabolism indexes OC,CT,tPINP,and BALP were higher in the observation group after treatment(t=4.21,t=3.05,t=2.66,t=3.16,P<0.05),while the iPTH andβ-CTX were lower(t=7.28,t=3.50,P<0.05).Conclusions:Vitamin D supplementation combined with suspended lumbar and abdominal muscle training can promote postoperative rehabilitation of OVCF patients and improve the level of bone metabolism indexes after surgery.

关 键 词：维生素D 骨质疏松性椎体压缩骨折 悬吊式腰腹肌训练 

分 类 号：R687.3[医药卫生—骨科学]