输卵管甲状腺肿的临床病理分析  

Clinicopathological features of struma in oviduct

作　　者：樊蕊蕊 高杰 FAN Rui-rui;GAO Jie(Department of Pathology,Xiang’an Hospital of Xiamen University,School of Medicine,Xiamen University,Xiamen 361002,China;Department of Pathology,Xiamen Humanity Hospital Fujian Medical University,Xiamen 361000,China)

机构地区：[1]厦门大学附属翔安医院病理科,厦门361002 [2]厦门弘爱医院病理科,厦门361000

出　　处：《诊断病理学杂志》2025年第2期117-120,共4页Chinese Journal of Diagnostic Pathology

基　　金：福建省自然科学基金计划资助项目(2023J01013);厦门市自然科学基金项目(3502Z20227118);厦门市医疗卫生指导性项目(3502720244ZD1156)。

摘　　要：目的总结输卵管甲状腺肿的病理特征、诊断、鉴别诊断、治疗及预后。方法回顾性收集并分析1例输卵管甲状腺肿患者的临床病理资料,通过HE染色和免疫组织化学染色等方法分析输卵管甲状腺肿的临床病理特征。结果患者女74岁。壶腹部与漏斗部交界处质稍硬,管腔内见1附壁结节,直径约0.9 cm,切面灰白、灰褐色,质中。镜下见一边界清楚、结节状生长的肿物,肿瘤由大小不一的甲状腺滤泡组成,滤泡腔内见嗜酸性胶质;高倍镜下,滤泡壁内可见立方上皮细胞衬附,未见重叠核、毛玻璃样核、核沟、核内包涵体,细胞无异型,表达TG;并于输卵管黏膜下见巢状分布的异位的门细胞,表达inhibin和AR。结论输卵管甲状腺肿罕见,临床易误诊,应与输卵管异位甲状腺、转移性甲状腺肿瘤等多种疾病相鉴别,影像学、组织形态及免疫组化等结果有助于诊断,治疗以手术切除为主,患者预后良好。Objective To investigate the clinicopathological features of the struma in oviduct.Methods Clinicopathological data of struma in oviduct were collected and analyzed by HE staining and immunohistochemistry.Results The patient was a 74-year-old woman.At the junction of the ampulla and the infundibular part,the texture was slightly hard,and there was a wall attachment nodule in the lumen,with a diameter of about 0.9 cm.Under the microscope,a tuberous tumor with clear boundary was seen.The tumor consisted of thyroid follicles of different sizes,and eosinophilic glia were seen in the follicular cavity.At high magnification,cubic epithelial cells were lined in the follicular wall,and no overlapping nuclei,ground-glass nuclei,nuclear trenches,or internal inclusion bodies were observed.The cells showed no atypia and expressed TG.Ectopic hilar cells were found in the submucosa of fallopian tube and expressed inhibin and AR.Conclusion Struma in oviduct is rare,which is difficult to identify and easy to be misdiagnosed.It should be differentiated from ectopic thyroid and metastatic thyroid tumors.Imaging,histomorphology and immunohistochemistry are helpful for the diagnosis.Surgical resection is the main treatment,and the prognosis is good.

关 键 词：输卵管畸胎瘤 甲状腺肿 组织病理 诊断 鉴别诊断 

分 类 号：R711.7[医药卫生—妇产科学]