2022年衢州市0~59岁人群乙型肝炎血清学现状分析  

Analysis on the serological status of hepatitis B among people aged 0-59 years in Quzhou City in 2022

作　　者：温婷翠 尹志英[2] 方泉均 富灿涯 郑灿杰[2] 龚晓英[2] 徐文杰 Wen Tingcui;Yin Zhiying;Fang Quanjun;Fu Canya;Zheng Canjie;Gong Xiaoying;Xu Wenjie(School of Public Health,Zhejiang Chinese Medical University,Hangzhou,Zhejiang 310053,China;不详)

机构地区：[1]浙江中医药大学公共卫生学院,浙江杭州310053 [2]衢州市疾病预防控制中心

出　　处：《中国公共卫生管理》2025年第1期131-134,共4页Chinese Journal of Public Health Management

基　　金：浙江省卫生健康科技计划临床研究应用项目(2022KY1354);中国肝炎防治基金会中国乙肝防控科研基金项目(YGFK20210003);中国肝炎防治基金会中国乙肝防控科研基金项目(YGFK20230058)。

摘　　要：目的了解衢州市0~59岁人群慢性乙型病毒性肝炎(以下简称乙肝)血清学现状并分析HBsAg阳性率的影响因素,为乙肝防控提供参考依据。方法采用分层随机抽样法,抽取衢州市柯城区、常山县0~59岁常住人口展开调查。应用SPSS 26.0软件对数据进行统计分析,采用二元logistic回归分析HBsAg阳性率的影响因素。结果共调查606人,HBsAb阳性率随年龄呈先下降后上升趋势(χ_(trend)^(2)=22.074,P<0.001)。控制性别、年龄之后,分层分析结果显示,常山县的HBsAg阳性率明显高于柯城区(χ_(MH)^(2)=19.077、18.213,P<0.001)。二元logistic回归分析结果显示,研究对象所在地区是0~59岁人群HBsAg阳性率的影响因素。结论衢州市实施乙肝疫苗接种成效明显,地区和年龄是影响乙肝防控的重要因素,应加强农村地区和成人乙肝防控。Objective To understand the serological status of hepatitis B among people aged 0-59 years in Quzhou City in 2022,and analyze the influencing factors of hepatitis B surface antigen(HBsAg)positivity rate,so as to provide reference for the prevention and control of hepatitis B.Methods A stratified random sampling method was used to select the resident population aged 0-59 years in Kecheng District and Changshan County of Quzhou City to conduct the questionnaire survey.SPSS 26.0 software was used for statistical analysis of the data,and binary logistic regression was used to analyze the influencing factors of HBsAg positivity rate.Results A total of 606 individuals were screened,HBsAb positivity rate showed a decreasing and then increasing trend with age(χ^(2) trend=22.074,P<0.001).After controlling for gender and age,HBsAg positivity was significantly higher in Changshan County than in Kecheng District(χ^(2) MH=19.077,18.213;P<0.001).Binary logistic analysis also showed that the area where the study subjects were located was an influential factor in the HBsAg positivity rate of people aged 0-59 years.Conclusion The implementation of hepatitis B vaccination in Quzhou has achieved remarkable results,region and age are the key factors affecting the prevention and control of hepatitis B,prevention and control of hepatitis B in rural areas and adults should be strengthened.

关 键 词：乙型肝炎 血清流行率 传染性疾病 

分 类 号：R512.62[医药卫生—内科学]