基于浊毒理论分型论治便秘型肠易激综合征  

Pattern Identification and Treatment of Constipation-Predominant Irritable Bowel Syndrome Based on the Turbidity Toxin Theory

作　　者：范诗苑 杨倩[2,3] 李佃贵 支政[2,3] 苏晓兰 李博林[2,3] FAN Shiyuan;YANG Qian;LI Diangui;ZHI Zheng;SU Xiaolan;LI Bolin(Graduate School,Hebei University of Chinese Medicine,Shijiazhuang,050091;Hebei Provincial Hospital of Traditional Chinese Medicine;Key Laboratory of Turbidity and Toxicity Syndrome in Hebei Province;Wangjing Hospital,China Academy of Chinese Medical Sciences)

机构地区：[1]河北中医药大学研究生院,河北省石家庄市050091 [2]河北省中医院 [3]河北省浊毒证重点实验室 [4]中国中医科学院望京医院

出　　处：《中医杂志》2025年第3期300-303,共4页Journal of Traditional Chinese Medicine

基　　金：国家科技部重点研发课题(2018YFC1704100,2018YFC1704102);国家中医临床研究基地建设项目(国中医药科技函[2018]131号);河北省重点研发计划(21377724D,21377740D);河北省“三三三人才工程”资助项目(C20221097);河北省政府资助临床医学优秀人才培养项目(ZF2023160)。

摘　　要：以浊毒理论为指导,认为浊毒壅滞致肠腑通降失常是便秘型肠易激综合征的关键病机,治疗以化浊毒、通肠腑为基本治则。临证分为浊毒蕴热、浊毒兼肝郁气滞、浊毒兼气阴两虚三种证型,分别运用自拟通腑降浊方清热通腑、泄浊解毒,自拟疏肝降浊方疏肝行气、降浊解毒,自拟麻枳降浊方益气滋阴、润肠化浊解毒。Guided by the turbidity toxin theory, it is believed that the key pathogenesis of constipation-predominant irritable bowel syndrome is the obstruction of turbidity toxin and the disruption of intestinal function. Treatment is based on the principles of dispelling turbidity toxin and promoting intestinal function. The clinical patterns can be divided into three types, turbidity toxin heat accumulation pattern, turbidity toxin combined with liver depression and qi stagnation pattern, and turbidity toxin combined with qi and yin deficiency pattern. The treatment can respectively use self-prescribed Tongfu Jiangzhuo Formula (通腑降浊方) to clear heat and unblock the bowels, direct the turbid downward and resolve toxins;use self-prescribed Shugan Jiangzhuo Formula (疏肝降浊方) to soothe the liver and move qi, direct the turbid downward and resolve toxins;use self-prescribed Mazhi Jiangzhuo Formula (麻枳降浊方) to boost qi and nourish yin, moisten the intestines to remove turbidity and resolve toxins.

关 键 词：肠易激综合征 便秘 浊毒 

分 类 号：R259[医药卫生—中西医结合]