基于“血浊理论”系统性探析五脏与阿尔茨海默病发病机制的相关性  

Systematical Exploration on Correlation between Five Zang-Organs and Pathogenesis ofAlzheimer′s Disease Based on Theory of Blood Turbidity

作　　者：王丹丹 王业飞[2] 韩萍 WANG Dandan;WANG Yefei;HAN Ping(First Clinical Medical College of Shandong University of Traditional Chinese Medicine,Jinan 250355,Shandong,China;Qingdao Institute of Bioenergy and Process,Chinese Academy of Sciences,Qingdao 266101,Shandong,China;Qingdao Hospital of Traditional Chinese Medicine,Qingdao 266033,Shandong,China)

机构地区：[1]山东中医药大学第一临床医学院,山东济南250355 [2]中国科学院青岛生物能源与过程研究所,山东青岛266101 [3]青岛市中医医院,山东青岛266033

出　　处：《辽宁中医杂志》2025年第3期28-30,I0002,共4页Liaoning Journal of Traditional Chinese Medicine

基　　金：国家自然科学基金项目(31872725);王新陆国医大师传承工作室(鲁财社指〔2022〕36);山东省自然科学基金面上项目(ZR2023MC066);山东省中医药科技发展项目面上项目(2021M115);山东能源研究院项目探索基金(SEI I202102);山东省中医药高层次人才培育项目专项经费资助项目(鲁卫中医药科教字〔2021〕6号)。

摘　　要：“浊生疾,清育康”,王新陆教授的“血浊理论”是新时代创新且成熟的中医理论,已逐渐成为当代诸多临床医生的共识,是适应现代疾病谱系的存在,阿尔茨海默病作为一种多因素的脑部疾病,其发病与血浊关系密切,浊则百病生,血浊神乱,与现代医学相比,中医具有多靶点、多中心的治疗特点,文章旨在通过血浊-五脏-神的串联关系来打破阿尔茨海默病聚焦于脑、肾的固有观点,冲破思维茧房,系统探析五脏与阿尔茨海默病发病机制的相关性,以期为阿尔茨海默病的防治提供新的临床思路。Alzheimer′s disease(AD)is a degenerative disease of the central nervous system characterized by progressive cognitive dysfunction and behavioral impairment.Its pathogenesis is more complex.Modern medicine believes that it is located in the brain,and the treatment target is single.The therapeutic effect is relatively limited.As an innovative and mature traditional Chinese medicine theory in the new era,blood turbidity is adapted to the existence of modern disease spectrum.It not only inherits and develops the basic theory of traditional Chinese medicine,but also has gradually become the consensus of many contemporary clinicians.Blood is not only one of the basic substances that constitute the human body and maintain the life activities of the human body,but also the core of the function of the five Zang-organs,and nourishes the spirit of the five Zang-organs.The purpose of this article was to break the inherent view of AD in the brain through the close relationship between blood turbidity,five Zang-organs and spirit,systematically analyzed the correlation between the five Zang-organs and the pathogenesis of AD and broke through the thinking cocoon,in order to provide new clinical ideas for the prevention and treatment of AD.

关 键 词：血浊 阿尔茨海默病 五脏 神 发病机制 

分 类 号：R256[医药卫生—中医内科学]