重症加强护理病房急性颅脑损伤患者发生下肢深静脉血栓的危险因素分析  

Risk factors analysis of lower extremity deep vein thrombosis in intensive care unit patients with acute traumatic brain injury

作　　者：陈慧 周晶 高雲 陈晨 Chen Hui;Zhou Jing;Gao Yun;Chen Chen(Intensive Care Unit,the First Affiliated Hospital with Nanjing Medical University(Jiangsu Province Hospital),Nanjing 210000,Jiangsu,China;Emergency trauma Ward,the First Affiliated Hospital with Nanjing Medical University(Jiangsu Province Hospital),Nanjing 210000,Jiangsu,China)

机构地区：[1]南京医科大学第一附属医院(江苏省人民医院)急诊监护病区,江苏南京210000 [2]南京医科大学第一附属医院(江苏省人民医院)急诊创伤病区,江苏南京210000

出　　处：《血管与腔内血管外科杂志》2025年第1期94-97,122,共5页Journal of Vascular and Endovascular Surgery

摘　　要：目的 探讨重症加强护理病房(ICU)急性颅脑损伤后发生下肢深静脉血栓(DVT)的危险因素。方法 收集2020年10月至2023年9月南京医科大学第一附属医院(江苏省人民医院)收治的176例ICU急性颅脑损伤患者的临床资料,根据住院期间下肢DVT发生情况将其分为DVT组(n=35)和对照组(n=141)。收集所有患者入院时的相关指标,采用Logistic回归模型分析急性颅脑损伤后发生下肢DVT的相关因素。结果 DVT组患者中13例无症状性DVT。DVT组患者的年龄、肥胖比例、昏迷比例、合并下肢创伤、使用机械通气比例均高于对照组患者,差异均有统计学意义(P<0.05)。多因素分析结果显示,老年(年龄≥60岁)、肥胖、昏迷、机械通气、合并下肢创伤均是ICU急性脑损伤患者发生下肢DVT的独立危险因素(P<0.05)。结论 急性颅脑损伤后存在一定的下肢DVT发生风险,部分患者为无症状性下肢DVT。老年(年龄≥60岁)、肥胖、昏迷、机械通气、合并下肢创伤均是ICU急性颅脑损伤患者发生下肢DVT的危险因素,可根据上述因素对急性颅脑损伤患者进行早期预防、早期干预。Objective To investigate the risk factors of deep vein thrombosis(DVT)in lower extremity after acute craniocerebral injury in intensive care unit(ICU).Method Clinical data of 176 patients with acute craniocerebral injury in ICU admitted to the First Affiliated Hospital with Nanjing Medical University(Jiangsu Province Hospital)from October 2020 to September 2023 were collected.According to the incidence of DVT in lower extremity during hospitalization,they were divided into DVT group(n=35)and control group(n=141).Relevant indicators of all patients at admission were collected,and Logistic regression model was used to analyze the related factors of lower extremity DVT after acute craniocerebral injury.Result In the DVT group,13 patients had asymptomatic DVT.The old age(age≥60 years old),obesity,coma,lower extremity trauma and mechanical ventilation in DVT group were higher than those in control group,with statistical significance(P<0.05).Multivariate analysis showed that old age,obesity,coma,mechanical ventilation and lower extremity trauma were independent risk factors for DVT in ICU patients with acute brain injury(P<0.05).Conclusion There is a certain risk of lower extremity DVT after acute craniocerebral injury,and some patients have asymptomatic lower limb DVT.Old age(age≥60 years old),obesity,coma,mechanical ventilation,and lower extremity trauma are all risk factors for lower extremity DVT in ICU patients with acute craniocerebral injury.Early prevention and intervention can be carried out according to the above factors.

关 键 词：重症加强护理病房 急性颅脑损伤 深静脉血栓 危险因素 

分 类 号：R543[医药卫生—心血管疾病]