联合干预对脑外伤患者住院期间下肢深静脉血栓的影响  

Effect of combined intervention on deep vein thrombosis of lower extremity in patients with brain injury during hospitalization

作　　者：赵小雪 唐慧娟[1] 蒋慧娟[1] 许伟[1] 张龙[1] 赵得银 Zhao Xiaoxue;Tang Huijuan;Jiang Huijuan;Xu Wei;Zhang Long;Zhao Deyin(Emergency Monitoring Room,Anhui Medical University Affiliated Suzhou Hospital,Suzhou 234000,Anhui,China;Department of General Surgery,Anhui Medical University Affiliated Suzhou Hospital,Suzhou 234000,Anhui,China)

机构地区：[1]安徽医科大学附属宿州市立医院急诊监护室,安徽宿州234000 [2]安徽医科大学附属宿州市立医院普外科,安徽宿州234000

出　　处：《血管与腔内血管外科杂志》2025年第1期127-130,144,共5页Journal of Vascular and Endovascular Surgery

摘　　要：目的 探讨联合干预对脑外伤患者住院期间发生下肢深静脉血栓的影响。方法 收集2022年8月至2023年8月安徽医科大学附属宿州市立医院收治的138例脑外伤患者的临床资料,按照观察期间是否采取了联合干预将其分为联合组(n=73)和对照组(n=65),比较两组患者住院期间下肢深静脉血栓发生率、出血率及感染率。结果 两组患者致伤原因、脑外伤的伤情、启动低分子肝素时间、使用呼吸机比例比较,差异均无统计学意义(P>0.05)。联合组患者下肢深静脉血栓发生率为1.4%(1/73),高于对照组患者的10.8%(7/65),差异有统计学意义(P<0.05)。两组患者出血率、感染率、死亡/自动出院比例比较,差异均无统计学意义(P>0.05)。结论 低分子肝素与间歇性气压治疗的联合干预可以安全有效降低脑外伤患者住院期间发生下肢深静脉血栓的风险,同时不增加并发症和不良结局的发生率,值得在临床上推广应用。Objective To investigate the effect of combined intervention on deep vein thrombosis of lower extremity in patients with brain injury during hospitalization.Method Clinical data of 138 patients with traumatic brain injury admitted to Anhui Medical University Affiliated Suzhou Hospital from August 2022 to August 2023 were collected.According to whether combined intervention was taken during the observation period,the patients were divided into combination group(n=73)and control group(n=65).The incidence rate of deep vein thrombosis,bleeding rate and infection rate of the two groups were compared during hospitalization.Result There were no significant differences in the cause of injury,severity of traumatic brain injury,initiation time of low molecular weight heparin and proportion of ventilator use between two groups(P>0.05).The incidence of lower extremity deep vein thrombosis in combination group was 1.4%(1/73),higher than that in control group of 10.8%(7/65),the difference was statistically significant(P<0.05).There were no significant differences in the bleeding rate,infection rate and death/automatic discharge ratio between the two groups(P>0.05).Conclusion The combined intervention of low molecular weight heparin and intermittent barotherapy can safely and effectively reduce the risk of lower extremity deep vein thrombosis in patients with brain trauma during hospitalization,without increasing the rate of complications and adverse outcomes,and is worthy of clinical promotion and application.

关 键 词：联合干预 脑外伤 深静脉血栓 

分 类 号：R543[医药卫生—心血管疾病]