2021—2023年成都市青白江区HIV抗体筛查结果分析  

Analysis of HIV antibody screening in Qingbaijiang District,Chengdu from 2021 to 2023

作　　者：周思敏 刘展志 徐仙 谭雅莉 段振华 薛晴 ZHOU Simin;LIU Zhanzhi;XU Xian;TAN Yali;DUAN Zhenhua;XUE Qing(Qingbaijiang District Center for Disease Control and Prevention,Chengdu,Sichuan 610300,China;不详)

机构地区：[1]成都市青白江区疾病预防控制中心,四川成都610300 [2]成都市疾病预防控制中心

出　　处：《中国国境卫生检疫杂志》2025年第1期56-59,共4页Chinese Journal of Frontier Health and Quarantine

基　　金：国家重大科技专项(2017ZX10103010);成都市医学科研项目(2023558)。

摘　　要：目的对成都市青白江区HIV抗体筛查有反应样本的补充试验结果进行分析,为艾滋病防控提供指导。方法依据《全国艾滋病检测技术规范(2020年修订版)》,对2021—2023年HIV抗体筛查试验有反应的样本采用免疫印迹法(WB)进行确证检测,用SPSS 21.0软件统计分析。结果HIV抗体筛查阳性样本508份,其中首次确证试验阳性358份(70.47%),不确定60份(11.81%),阴性90份(17.72%)。确证阳性中出现频率最高的条带是gp160和gp120,均为100.00%,不确定样本中出现率最高的条带是p24,有58.33%。不确定样本中,成功随访55人,其中转阳15人,转阴34人,6人仍为不确定。筛查试验单试剂和双试剂有反应组的确证阳性率差异有统计学意义(P<0.001)。在373份确证阳性样本中,男性确证阳性率高于女性,差异有统计学意义(χ^(2)=59.993,P<0.001)。阳性确证者主要来自门诊及住院病人,确证阳性率72.97%。结论在实际工作中应加强对HIV抗体检测和质量控制,加强对中老年男性人群的艾滋病健康教育力度和不确定病例的随访,遏制疫病蔓延。Objective To analyze the supplementary test results of HIV antibody screening response samples in Qingbaijiang,Chengdu,and to provide guidance for AIDS prevention and control.Methods According to the"National Guideline for Detection of HIV/AIDS in China(2020 Revision)",the response samples of HIV antibody screening from 2021 to 2023 were confirmed by Western blot(WB).SPSS 21.0 software was used for statistical analysis.Results A total of 508 samples were screened for HIV antibody,among which 358 were positive(70.47%),60 were indeterminate(11.81%),90 were negative(17.72%).In the HIV antibody positive samples,band gp160 and gp120 appeared most frequently(100.00%).In the indeterminate samples,the positive rate of band p24 was the highest(58.33%).Among 60 samples with HIV indeterminate results,only 55 were followed up with HIV detection,of which 15 converted to be HIV antibody positive,34 were negative and 6 remained to be indeterminate.The positive rate of screening test was significantly different between single-reagent response group and the dualreagent response group(P<0.001).Among the 373 confirmed positive samples,the confirmed positive rate was higher in males than in females,and the difference was statistically significant(χ^(2)=59.993,P<0.001).The majority of positive samples were from outpatients and inpatients,and the confirmatory positive rate was 72.97%.Conclusion In practical application,it was essential to enhance HIV antibody testing and quality control.Additionally,it was need to intensify AIDS health education at middle-aged and elderly men,as well as implement follow-up procedures for indeterminate cases in order to stop the spread of the disease.

关 键 词：艾滋病 初筛 补充试验 免疫印迹法 

分 类 号：R512.911[医药卫生—内科学]