样品基质对吸附管采样-热脱附-气相色谱-质谱法测定挥发性有机化合物的影响  

Effect of Sample Matrix on Determination of Volatile Organic Compounds by Adsorption Tube Sampling-Thermal Desorption-Gas Chromatography-Mass Spectrometry

作　　者：董翊[1] 姜阳[1] 于瑞祥[1] 高艳秋[1] 任逸尘 魏王慧 DONG Yi;JIANG Yang;YU Ruixiang;GAO Yanqiu;REN Yichen;WEI Wanghui(Shanghai Institute of Measurement and Testing Technology,Shanghai 201203,China)

机构地区：[1]上海市计量测试技术研究院,上海201203

出　　处：《理化检验(化学分册)》2025年第2期143-148,共6页Physical Testing and Chemical Analysis(Part B:Chemical Analysis)

基　　金：上海市市场监督管理局科技项目(2021-16)。

摘　　要：用氮气稀释含有丙酮、异丙醇、正己烷、乙酸乙酯、苯等5种挥发性有机化合物(VOCs)的混合标准气体制备标准吸附管系列,采用热脱附-气相色谱-质谱法测定并绘制工作曲线,以考察空气、二氧化碳、甲醇基质对低、中、高含量上述5种VOCs测定的影响。结果显示:5种VOCs的质量在不同范围内和对应的定量离子的峰面积呈线性关系,检出限(3S/N)为0.0300~1.00 ng,测定值的相对标准偏差(n=7)为2.1%~5.7%;除甲醇基质中低含量丙酮和异丙醇的回收率大于200%外,3种基质中不同含量的5种VOCs的回收率均在90.0%~110%内,推测残留在检测器中的甲醇影响了与甲醇保留时间接近的丙酮和异丙醇的电离,导致离子强度增大,回收率增加。A standard adsorption tube series was prepared by diluting the mixed standard gas containing 5 volatile organic compounds(VOCs)including acetone,isopropyl alcohol,n-hexane,ethyl acetate,and benzene with nitrogen gas.The method of thermal desorption-gas chromatography-mass spectrometry was used for determination and plotting the working curve,and effects of matrices,including air,carbon dioxide,and methanol,on determination of the 5 VOCs with low,medium,and high contents were investigated.It was shown that linear relationships between values of the masses of the 5 VOCs and peak areas of the corresponding quantitative ions were kept in definite ranges,with detection limits(3S/N)in the range of 0.0300-1.00 ng,and RSDs(n=7)of the determined values in the range of 2.1%-5.7%.Except for the recovery of acetone and isopropyl alcohol with the low content in methanol matrix,which was greater than 200%,the recovery of the 5 VOCs with different contents in the 3 matrices was all within 90.0%-110%.It was speculated that the residual methanol in the detector affected the ionization of acetone and isopropyl alcohol,retention time of which was close to that of methanol,resulting in an increase in ion intensity and recovery.

关 键 词：吸附管采样 热脱附 气相色谱-质谱法 挥发性有机化合物 基质影响 甲醇 

分 类 号：O657.63[理学—分析化学]