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作 者:中华医学会器官移植学分会 中华医学会外科学分会外科手术学学组 中华医学会外科学分会移植学组 华南劈离式肝移植联盟 傅斌生 冯啸 刘剑戎 任杰 王劲 易述红[2] 杨扬[2] Chinese Society of Organ Transplantation of Chinese Medical Association;Surgery Group of Chinese Society of Surgery of Chinese Medical Association;Transplantation Group of Chinese Society of Surgery of Chinese Medical Association;South China Alliance of Split Liver Transplantation;Yi Shuhong;Yang Yang(不详;Department of Hepatic Surgery,Liver Transplantation Center,the Third Affiliated Hospital of Sun Yat-sen University,Institute of Organ Transplantation,Sun Yat-sen University,Guangdong Provincial Key Laboratory of Liver Disease,Guangdong Transplantation Medical Engineering Laboratory,Guangzhou 510630,China)
机构地区:[1]不详 [2]中山大学附属第三医院肝脏外科暨肝移植中心、中山大学器官移植研究所、广东省肝脏疾病研究重点实验室、广东省移植医学工程实验室,广州510630
出 处:《器官移植》2025年第2期191-201,共11页Organ Transplantation
基 金:国家重点研发计划项目(2017YFA0104304);国家自然科学基金(81972286、82073171);广东省自然科学基金(2020A1515010574、2020A1515010302);广东省科技计划项目(2019B020236003、2020B1212060019)。
摘 要:肝移植是治疗儿童终末期肝病的有效手段,疗效确切。劈离式肝移植能有效扩大儿童供肝来源,劈离式供肝儿童肝移植具有特殊临床特点和规律,建立劈离式供肝儿童肝移植技术操作规范对提高疗效具有重要意义。本文从供者和供肝评估、供受体匹配、供肝管道的分割与重建方面形成劈离式供肝儿童肝移植临床操作指南,旨在规范劈离式供肝儿童肝移植的技术流程,优化手术细节,降低并发症发生率,进而促进我国劈离式供肝儿童肝移植快速发展。Liver transplantation is an effective treatment for end-stage liver disease in children,and its clinical efficacy has been validated.Split liver transplantation can effectively expand the donor liver pool for children.Split liver transplantation for children has specific clinical characteristics and principles.Establishing technical operation specifications for pediatric split liver transplantation plays a significant role in improving clinical efficacy.In this article,clinical practice guidelines on pediatric split liver transplantation was established in the aspect of donor and donor liver evaluation,donor-recipient matching,and ductal segmentation and reconstruction of donor liver,aiming to standardize the technical process,optimize surgical procedures,reduce the incidence of complications of split liver transplantation for children,further promoting rapid development of pediatric split liver transplantation in China.
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