于世家教授治疗消渴病的中药组方规律研究  

A study on Professor YU Shijia’prescription rule in treating diabetes

作　　者：商洪伟 刘松岩[2] 刘小溪[2] 于世家[2] 霍晶晶[2] SHANG Hongwei;LIU Songyan;LIU Xiaoxi;YU Shijia;HUO Jingjing

机构地区：[1]辽宁中医药大学,辽宁沈阳110847 [2]辽宁中医药大学附属医院,辽宁沈阳110032

出　　处：《中医临床研究》2024年第33期54-59,共6页Clinical Journal Of Chinese Medicine

基　　金：全国名老中医药专家传承工作室建设项目(国中医药人教函[2022]75号)。

摘　　要：目的:运用中医传承计算平台V3.0探讨于世家教授治疗消渴病的临床思维和选方用药,分析总结其核心类方。方法:通过门诊病历采集的方式收集于世家教授2019年7月―2021年6月在辽宁中医药大学附属医院门诊诊治的消渴病医案,按照纳入排除标准进行筛选,收集患者病历信息,建立“于世家-消渴病”病历数据库,以中医传承计算平台V3.0软件作为数据挖掘工具,利用其方剂分析等功能进行数据挖掘,分析组方规律。结果:共纳入255个病历,涉及药物共122味,使用频次排在前10位的分别是黄芪、丹参、红花、鸡血藤、赤芍、知母、女贞子、黄精、当归、枸杞子,四气以温、寒、平为主,五味以甘、苦、辛为主,归经以肝经、肾经、脾经为主,功效以补虚类、活血化瘀类、清热类为主,常用药物组合21条,通过聚类分析得到核心类方3个,类方1由黄芪、车前子、薏苡仁、猪苓、生地黄组成,类方2由红花、鸡血藤、黄芪、丹参、三七组成,类方3由女贞子、丹参、黄芪、枸杞子、知母组成。结论:于世家教授坚持治病求本,主张将补气活血法贯穿于消渴病治疗始终,并提炼出3个核心类方,构思严谨,药力平和,可应用于消渴病的不同阶段,为消渴病的治疗提供新思路。Objective:To explore Professor YU Shijia’s clinical thinking and prescription selection and medication in the treatment of diabetes by Traditional Chinese Medicine Inheritance Computer System V3.0,and to analyze and summarize the core prescriptions.Methods:Medical records of diabetes treated by Professor YU Shijia in the Outpatient Department of the Affiliated Hospital of Liaoning University of Traditional Chinese Medicine from July 2019 to June 2021 were collected by means of outpatient medical records collection.According to the inclusion and exclusion criteria,the patients’medical record information was collected to establish the medical record database of‘YU Shijia-Diabetes Disease’,Traditional Chinese Medicine Inheritance Computer System V3.0 software was used as a data mining tool to analyze the prescription patterns by formula analysis and other functions.Results:A total of 255 medical records were included,with a total of 122 flavors of medicinals,and the top 10 in frequency of use were Huangqi(Astragalus membranaceus),Danshen(Salvia miltiorrhiza),Honghua(Safflower),Jixueteng(Caulis Spatholobi),Chishao(Radix Paeoniae),Zhimu(Radix Rhizome),Nvzhenzi(Fructus ligustris),Huangjing(Rhizoma polygonati),Danggui(Angelica sinensis),and Gouqizi(Fruit of Chinese wolfberry).The four properties were mainly warm,cold,and moderate,the five flavors were mainly sweet,bitter,and pungent;the channel tropism was mainly liver meridian,kidney meridian,and spleen meridian.The medicine with efficacy of supplementing deficiency,promoting blood circulation and removing blood stasis,and clearing heat were mainly used in 21 commonly used drug combinations,and 3 core prescriptions were obtained through cluster analysis.Formula 1 was composed of Huangqi,Cheqianzi(plantaglio seed),Yiyiren(Coix seed),Zhuling(Poria pora)and Shengdihuang(Radix rehmanniae);Formula 2 was composed of Honghua,Jixueteng,Huangqi,Danshen and Sanqi(Notoginseng);Formula 3 was composed of Nvzhenzi,Danshen,Huangqi,Gouqizi,and Zhimu.Conclusion:Professor YU Shi

关 键 词：学术思想 中医传承计算平台 消渴病 数据挖掘 

分 类 号：R255..4[医药卫生—中医内科学]