高分辨率磁共振成像下颈动脉斑块特征与空腹血糖异常的关系  

Characteristics of carotid plaque and its relationship with abnormal fasting blood glucose under high-resolution magnetic resonance imaging

作　　者：董兰真 吴婧 孙学瑞 于洋 刘鹏 DONG Lanzhen;WU Jing;SUN Xuerui;YU Yang;LIU Peng(Cangzhou People’s Hospital,Cangzhou 061000,China)

机构地区：[1]沧州市人民医院,河北沧州061000

出　　处：《中国实用神经疾病杂志》2025年第4期448-452,共5页Chinese Journal of Practical Nervous Diseases

基　　金：沧州市重点研发计划项目(编号:213106030)。

摘　　要：目的探究高分辨率磁共振成像下颈动脉斑块特征,分析其与青年患者空腹血糖异常的关系。方法选取2022-01—12沧州市人民医院收治的120例青年脑卒中患者为研究对象。根据患者的空腹血糖水平分为正常组(77例)和糖耐量异常组(43例),所有患者均进行颈动脉超声检查,总结高分辨率磁共振成像下颈动脉斑块特征,分析颈动脉斑块与空腹血糖水平的关系。结果糖耐量异常组患者冠心病、吸烟史、同型半胱氨酸(Hcy)、低密度脂蛋白(LDL)与正常组患者相比有统计学差异(P<0.05)。糖耐量异常组患者的平均管腔面积、平均管壁面积、管腔狭窄程度、斑块内钙化及颈动脉斑块与正常组相比均有统计学差异(P<0.05)。多因素Logistic回归分析显示,冠心病、吸烟史、Hcy、LDL、平均管腔面积、平均管壁面积、管腔狭窄程度、斑块内钙化及颈动脉斑块为影响青年脑卒中患者空腹血糖的危险因素(P<0.05)。Pearson分析显示,青年脑卒中患者的空腹血糖与平均管壁面积、管腔狭窄程度、斑块内钙化及颈动脉易损斑块呈正相关(分别为r=0.622、0.569、0.489、0.636,P<0.05),与平均管腔面积呈负相关(r=-0.537,P<0.05)。结论高分辨率磁共振成像下不同空腹血糖水平青年脑卒中患者的颈动脉斑块特征具有一定差异,青年脑卒中患者的空腹血糖水平与颈动脉斑块特征有一定相关性。Objective To investigate the characteristics of carotid artery plaques under high-resolution magnetic resonance imaging,and analyze its relationship with abnormal fasting blood sugar in young patients.Methods Totally 120 young stroke patients admitted to the Cangzhou People’s Hospital from January 2022 to December 2022 were selected as the study objects.Patients were divided into normal group(77 cases)and abnormal glucose tolerance group(43 cases)according to their fasting blood glucose level.Carotid artery ultrasound examination was performed on all patients.The characteristics of carotid artery plaque under high-resolution magnetic resonance imaging were summarized,and the relationship between carotid plaque and fasting blood glucose level was analyzed.Results Coronary heart disease,smoking history,homocysteine(Hcy)and low density lipoprotein(LDL)in the abnormal glucose tolerance group were significantly different from those in the normal group(P<0.05).The mean lumen area,mean tube wall area,lumen stenosis degree,intracavicular calcification and carotid plaque of patients in the abnormal glucose tolerance group had certain differences compared with those in the normal group(P<0.05).Multivariate Logistic regression analysis showed that coronary heart disease,smoking history,Hcy,LDL,mean lumen area,mean tube wall area,stenosis degree of lumen,intracavity calcification and carotid plaque were risk factors for abnormal fasting blood glucose in young stroke patients(P<0.05).Pearson analysis showed that fasting blood glucose in young stroke patients was positively correlated with mean tube wall area,lumen stenosis,intracavity calcification and vulnerable carotid plaque(r=0.622,0.569,0.489,0.636,respectively,P<0.05),and negatively correlated with mean lumen area(r=-0.537,P<0.05).Conclusion There are certain differences in the characteristics of carotid plaque in young stroke patients with different fasting blood glucose levels under high-resolution magnetic resonance imaging,and there is a certain correlation betwee

关 键 词：磁共振成像 颈动脉斑块 超声 空腹血糖 脑卒中 青年 

分 类 号：R445.2[医药卫生—影像医学与核医学] R543.4[医药卫生—诊断学]