透穴九针穴位埋线疗法联合泮托拉唑治疗难治性胃食管反流病临床研究  

Clinical Study on Catgut Embedment in Acupoint with Through-Acupoint Nine-Needle Combined with Pantoprazole for Refractory Gastroesophageal Reflux Disease

作　　者：施一春[1] 王美樱 汪玲羽[1] 陈利芳[1] SHI Yichun;WANG Meiying;WANG Lingyu;CHEN Lifang(The Third Affiliated Hospital of Zhejiang Chinese Medical University,Hangzhou Zhejiang 310005,China;The Third School of Clinical Medicine,Zhejiang Chinese Medical University,Hangzhou Zhejiang 310053,China)

机构地区：[1]浙江中医药大学附属第三医院,浙江杭州310005 [2]浙江中医药大学第三临床医学院,浙江杭州310053

出　　处：《新中医》2025年第5期126-129,共4页New Chinese Medicine

基　　金：王樟连全国名老中医药专家传承工作室建设项目(国中医药人教函〔2022〕75号);浙江省中医药科技计划项目(2017ZB053)。

摘　　要：目的:观察透穴九针穴位埋线疗法联合泮托拉唑治疗难治性胃食管反流病(RGERD)的临床疗效。方法:选取2020年1月—2022年12月在浙江中医药大学附属第三医院接受治疗的70例RGERD患者,按随机数字表法分为试验组和对照组各35例。对照组给予泮托拉唑钠肠溶片口服治疗,试验组在对照组基础上给予透穴九针穴位埋线疗法治疗,2组均治疗8周,随访12周。比较2组临床疗效、反流性疾病问卷量表(RDQ)评分、GERD相关生活质量量表(GERD-HRQL)评分及安全性。结果:试验组总有效率93.10%(27/29),高于对照组66.67%(20/30)(P<0.05)。治疗后、随访时,2组RDQ评分、GERD-HRQL评分均较治疗前降低,试验组RDQ评分、GERD-HRQL评分均低于同期对照组(P<0.05),安全性良好。结论:透穴九针穴位埋线疗法联合泮托拉唑治疗RGERD,较单用泮托拉唑口服在改善临床症状和减少复发方面效果更好,安全性高。Objective:To observe the clinical effect of catgut embedment in acupoint with through-acupoint nineneedle combined with Pantoprazole on refractory gastroesophageal reflux disease(RGERD).Methods:A total of 70 cases of RGERD patients treated at the Third Affiliated Hospital of Zhejiang Chinese Medical University from January 2020 to December 2022 were divided into the trial group and the control group according to the random number table method,with 35 cases in each group.The control group was given the oral administration of Pantoprazole Sodium Enteric-Coated Tablets,and the trial group was additionally treated with catgut embedment in acupoint with throughacupoint nine-needle based on the treatment of the control group.Both groups were treated for eight weeks and followed up for 12 weeks.Clinical effects,Reflux Disease Questionnaire(RDQ)scores,GERD-Health Related Quality of Life(GERD-HRQL)scores and safety profile were compared between the two groups.Results:The total effective rate in the trial group was 93.10%(27/29),higher than 66.67%(20/30)in the control group(P<0.05).After treatment and during follow-up,RDQ scores,and GERD-HRQL scores in the two groups were reduced when compared with those before treatment,with the trial group showing lower scores than the control group at the same time points(P<0.05).The safety profile was good.Conclusion:The catgut embedment in acupoint with through-acupoint nine-needle combined with Pantoprazole is more effective than Pantoprazole alone in improving clinical symptoms and reducing recurrence in the treatment of RGERD,with a high safety profile.

关 键 词：难治性胃食管反流病 穴位埋线 透穴九针 

分 类 号：R246[医药卫生—针灸推拿学]