单支架联合药物球囊处理中低危左主干真分叉病变的可行性研究  

Feasibility of Single Stent Combined with DCB Treatment for Low-Risk Left Main Trunk Bifurcation Lesions

作　　者：刘江 祝风涛 赖晶 彭桢明 申艳林 柯小云 童金英 LIU Jiang;ZHU Feng-tao;LAI Jing;PENG Zhen-ming;SHEN Yan-lin;KE Xiao-yun;TONG Jin-ying(Department of Cardiovascular Medicine,Yingtan People’s Hospital,Jiangxi Province,Jiangxi Yingtan 335000)

机构地区：[1]江西省鹰潭市人民医院心血管内科,江西鹰潭335000

出　　处：《中国医疗器械信息》2025年第4期21-23,共3页China Medical Device Information

基　　金：鹰潭市科技局项目(项目名称:药物涂层支架联合药物球囊处理低中危风险左主干分叉病变,项目编号:Ykz2022074)。

摘　　要：目的:研究单支架联合药物球囊处理中低危左主干真分叉病变的可行性。方法:回顾性选取2021年1月~2023年7月鹰潭市人民医院收治的经血管内超声(IVUS)指导处理左主干真性分叉病变45例,分为两组,其中双支架组18例,左主干的左回旋支、左前降支都放入支架;药物球囊组27例,左主干的左回旋支实施药物球囊扩张,左前降支放入支架。对比两组的治疗效果。结果:从年龄、性别、家族史、吸烟史、体质量指数(BMI)、血肌酐(Scr)、低密度脂蛋白胆固醇(LDL-C)、总胆固醇(TC)、高血压、糖尿病来看,双支架组和药物球囊组差异有统计学意义(P<0.05);术前及术后左主干、前降支、回旋支狭窄程度、最小管腔面积,1年内MACE事件发生率和管腔再狭窄率,两组差异有统计学意义(P<0.05);从手术时间、造影剂用量、围术期并发症发生率、手术完成率来看,药物球囊组优于双支架组,差异有统计学意义(P<0.05)。结论:对于处理中低危左主干真分叉病变,药物球囊组与双支架组对比,药物球囊组术后即刻及术后1年MACE事件发生率不劣于双支架组,而手术时间,射线量,手术完成率及围术期并发症发生率明显优于双支架组。Objective:To investigate the feasibility of using a single stent combined with DCB to treat low-risk left main trunk bifurcation lesions.Methods:A retrospective study was conducted on 45 cases of true bifurcation lesions of the left main trunk treated with intravascular ultrasound(IVUS)guidance at Yingtan People's Hospital from January 2021 to July 2023.The patients were divided into two groups,including 18 cases in the double bracket group,in which stents were placed in the left circumflex branch and left anterior descending branch of the left main trunk;In the medication balloon group of 27 cases,medication balloon dilation was performed on the left circumflex branch of the left main trunk,and a stent was placed on the left anterior descending branch.Compared the treatment effects of the two groups.Results:In terms of age,gender,family history,smoking history,body mass index(BMI),serum creatinine(Scr),lowdensity lipoprotein cholesterol(LDL-C),total cholesterol(TC),hypertension,and diabetes,there were significant differences between the double stent group and the drug balloon group(P<0.05);The degree of stenosis and minimum lumen area of the left main trunk,anterior descending branch,and circumflex branch before and after surgery,as well as the incidence of MACE events and lumen restenosis within 1 year,showed statistically significant differences between the two groups(P<0.05);In terms of surgical time,contrast agent dosage,incidence of perioperative complications,and surgical completion rate,the drug balloon group was superior to the double bracke group,and the difference was statistically significant(P<0.05).Conclusion:For the treatment of low-risk left main trunk true bifurcation lesions,compared with the double bracket group,the incidence of MACE events immediately and 1 year after surgery in the drug balloon group was not inferior to that in the double stent group.However,the surgical time,radiation dose,surgical completion rate,and perioperative complication rate were significantly better in the drug ball

关 键 词：中低危险左主干真分叉 血管内超声 单支架联合药物球囊 双支架 

分 类 号：R541[医药卫生—心血管疾病]