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作 者:付瑜 FU Yu(Nuclear Magnetic Laboratory,Jinghai District Hospital,Tianjin,Tianjin 301600)
出 处:《中国医疗器械信息》2025年第4期92-94,共3页China Medical Device Information
摘 要:目的:探讨3.0核磁共振(MRI)对卵巢子宫内膜异位囊肿(Ovarian endometriotic cyst,OEC)的临床诊断价值及MRI影像学特点。方法:回顾性分析本院收治并经手术治疗病理确诊的OEC患者25例,畸胎瘤(OMCT)18例,所有患者术前均行妇科超声及3.0MRI检查及血清CA125和CA199水平的检测。结果:MRI与妇科超声对卵巢子宫内膜异位囊肿诊断的敏感性分别为80.0%和40.0%,特异性分别为72.2%和16.6%;25例卵巢子宫内膜异位囊肿患者共检出52个病灶,5例患者为单侧卵巢病变,20例为双侧。囊肿大小直径0.5~14cm,以圆形和类圆形为主,少部分为不规则形状可见“卫星囊”样改变;52个病灶中有44个呈现T1WI高信号,6个病灶表现为低信号。时间反转恢复(STIR)序列,原为T1WI高信号的病灶未见明显减低。OEC患者与OMCT患者的血清CA125分别为(99.9±49.4)μg/mL和(58.9±32.9)μg/mL,血清CA199分别为(160.5±108.6)μg/mL和(75.1±52.1)μg/mL,OEC显著高于OMCT组,且差异有统计学意义(P<0.05);分别以血清CA125和CA199为参考诊断OEC的敏感性为72.2%和77.8%,特异性分别为60.0%和64.0%,ROC曲线下面积AUC分别为0.74(95%CI:0.59~0.88)和0.77(95%CI:0.63~0.91)。结论:3.0核磁共振对卵巢子宫内膜异位囊肿的诊断敏感性和特异性均较高。Objective:To explore the clinical diagnostic value and MRI imaging characteristics of 3.0 magnetic resonance imaging(MRI)for ovarian endometrial cysts(OEC).Methods:A retrospective analysis was conducted on 25 patients with OEC and 18 patients with cystic teratoma(OMCT)who were diagnosed by surgery and pathology in our hospital.All patients underwent gynecological ultrasound and 3.0 MRI examination before surgery.At the same time,serum CA125 and CA199 levels were measured in OMCT and OEC cases.Results:The sensitivity and specificity of MRI and gynecological ultrasound in the diagnosis of ovarian endometriotic cysts were 80.0%and 40.0%,respectively,and 72.2%and 16.6%,respectively;A total of 52 lesions were detected in 25 patients with ovarian endometriotic cysts,with 5 patients having unilateral ovarian lesions and 20 patients having bilateral lesions.The cyst has a diameter ranging from 0.5-14cm,mainly circular and quasi circular in shape,with a small portion showing irregular shapes and satellite like changes;Out of 52 lesions,44 showed high signal intensity on T1WI and 6 lesions showed low signal intensity.The time reversal recovery(STIR)sequence showed varying degrees of reduced signal intensity in lesions that were originally high signal on T1WI.The serum CA125 levels in OEC patients and OMCT patients were(99.9±49.4)μg/mL,respectively and(58.9±32.9)μg/mL,serum CA199 values were(160.5±108.6)μg/mL,respectively and(75.1±52.1)μg/mL,OEC was significantly higher than OMCT group,and the difference was statistically significant(P<0.05);The sensitivity and specificity for diagnosing OEC using serum CA125 and CA199 as reference were 72.2%and 77.8%,60.0%and 64.0%,respectively.The AUC under the ROC curve was 0.74(95%CI:0.59-0.88)and 0.77(95%CI:0.63-0.91),respectively.Conclusion:3.0 magnetic resonance imaging has high diagnostic sensitivity and specificity for ovarian endometriotic cysts.
关 键 词:核磁共振 卵巢子宫内膜异位囊肿 诊断 ROC曲线
分 类 号:R445.2[医药卫生—影像医学与核医学]
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