Exploration of the Value of Extract of Wuwei Xiaodu Drink on Rabbit Model of Spinal Infection  

作　　者：Qing Wang Ying Zhan Jianhua Zhang Zheng Song Xiuping Li Qiang Zhang 

机构地区：[1]Shandong Public Health Clinical Center,Shandong University,Shandong 250013,China

出　　处：《Journal of Clinical and Nursing Research》2025年第2期1-6,共6页临床护理研究(英文)

基　　金：Shandong Province Traditional Chinese Medicine Science and Technology Project Task Book Number(Project No.:M-2022178);2024 Shandong Provincial Traditional Chinese Medicine Science and Technology Project(Project No.:Z20242407)。

摘　　要：Objective:To study the therapeutic effect of the Extract of Wuwei Xiaodu Drink on spinal infection and provide the scientific basis for clinical application.Methods:By establishing a rabbit model of spinal infection,this paper observed and analyzed the changes in body mass before and after the intervention and the comparison of inflammation-related factors and blood leukocyte counts among the three groups.Results:There was a significant difference in the changes in body mass of rabbits before and after intervention in the experimental group,control group and blank group(P<0.05);there was no statistically significant difference in calcitoninogen,C-reactive protein and routine blood leukocyte counts between the experimental group and the control group(P>0.05),and there was a statistically significant difference in calcitoninogen,C-reactive protein and routine blood leukocyte counts between the experimental group and the blank group(P<0.05).Conclusion:The Extract of Wuwei Xiaodu Drink can play a protective role by regulating the level of inflammatory factors in blood routine leukocyte count and reducing the inflammatory reaction in the spinal cord injury area.

关 键 词：Extract of Wuwei Xiaodu Drink Spinal infection Rabbit model 

分 类 号：R33[医药卫生—人体生理学]