The Role of Central Inflammation in Postoperative Cognitive Dysfunction  

作　　者：Wenyuan Zhang Fang Yan 

机构地区：[1]Department of Basic Medicine,Kangda College of Nanjing Medical University,Lianyungang 22200,Jiangsu Province,China

出　　处：《Journal of Clinical and Nursing Research》2025年第2期35-39,共5页临床护理研究(英文)

基　　金：Jiangsu University Student Innovation and Entrepreneurship Project,“Study on the Mechanism of TLR4-mediated Central Inflammation Induced by Glial Cell Activation to POCD”(Project No.:202313980027Y)。

摘　　要：Postoperative cognitive dysfunction is a typical complication,which can be referred to as POCD.This complication is common in elderly patients.Among them,POCD is mainly manifested in the function of patients with attention deficit and memory reduction after surgery,among which serious patients are prone to personality change,which affects their social behavior ability.In the context of the current era,the cause of POCD is not clear,combined with the results of most studies,it is found that central nervous inflammation,is a key factor affecting POCD.From the perspective of central inflammation,this paper analyzes the relationship between central inflammation and POCD,and discusses the mechanism of action,aiming at effectively preventing and treating POCD and providing a reference for subsequent research in related fields.

关 键 词：Central inflammation Postoperative cognitive dysfunction EFFECTS 

分 类 号：R61[医药卫生—外科学]