羟基红花黄色素A保肝作用研究进展  

Research progress on hepatoprotective effects of hydroxysafflor yellow A

作　　者：艾楠 王馨晨 刘星宇 刘庆 王锐[2] 杨婧[1] AI Nan;WANG Xinchen;LIU Xingyu;LIU Qing;WANG Rui;YANG Jing(Basic Medical College,Heilongjiang University of Chinese Medicine,Harbin 150040,China;School of Pharmacy,Heilongjiang University of Chinese Medicine,Harbin 150040,China)

机构地区：[1]黑龙江中医药大学基础医学院,黑龙江哈尔滨150040 [2]黑龙江中医药大学药学院,黑龙江哈尔滨150040

出　　处：《现代药物与临床》2025年第1期229-233,共5页Drugs & Clinic

基　　金：国家自然科学基金资助项目(81603418);黑龙江省优秀人才项目(2020YQ05)。

摘　　要：羟基红花黄色素A是红花中主要生物活性成分,具有广泛的生物学作用。羟基红花黄色素A通过抗炎、抗氧化应激、抗肝纤维化、抗肝癌、调节肝脏代谢和延缓肝细胞衰老发挥保肝作用。梳理了羟基红花黄色素A保肝作用的研究进展,以期为羟基红花黄色素A的保肝作用的临床应用提供参考。Hydroxysafflor yellow A is the main bioactive component in Carthami Flos,and has a wide range of biological effects.Hydroxysafflor yellow A exerts hepatoprotective effects by anti-inflammatory effect,antioxidant stress,anti-liver fibrosis,anti-liver cancer,regulating liver metabolism,and anti-aging effects.This article reviews the research progress on hepatoprotective effects of Hydroxysafflor yellow A,in order to provide reference for clinical application of Hydroxysafflor yellow A's hepatoprotective effects.

关 键 词：羟基红花黄色素A 保肝作用 抗炎 抗氧化应激 抗肝纤维化 抗肝癌 肝脏代谢 肝细胞衰老 

分 类 号：R285.5[医药卫生—中药学]